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RO-5323441

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P991430
    RO5323441

    TB-403

    		 VEGFR Cancer
    RO5323441 (TB-403) is a human IgG1 monoclonal antibody (mAb) targeting PLGF. RO5323441 inhibits the binding of human PlGF-1 or PlGF-2 to VEGFR-1 (IC50 values are 0.1 and 0.2 nM, respectively). RO5323441 blocks PlGF-induced VEGFR-1 phosphorylation in Flt-1-transfected HEK293 cells. RO5323441 has antitumor activity .
    RO5323441

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