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RLM

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LRRK2 (1)
By Research Areas:	Neurological Disease (1)

1

Inhibitors & Agonists

4

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

SRI-31255	LRRK2	Neurological Disease
SRI-31255 is an orally active LRRK2 inhibitor with IC₅₀ values of 520 and 427 nM for human wild-type (WT) and mutant G2019S, respectively. SRI-31255 exerts neuroprotective effects by binding to the ATP-binding pocket of LRRK2, inhibiting kinase activity. SRI-31255 can be used as a lead compound for the development of LRRK2-targeted drugs for the treatment of Parkinson's disease .

Species:	Human (1) Mouse (1) Canine (2)
Tag:	His (3) Fc (1)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source

	IL-17RD Protein, Canine (HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, His) is produced in HEK293 cells with a His-Terminal Fc-tag.

	IL-17RD Protein, Human (HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Human	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

	IL-17RD Protein, Mouse (HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Mouse	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

	IL-17RD Protein, Canine (HEK293, Fc) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

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