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QO-40

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130070
    QO-40

    		Potassium Channel Neurological Disease
    QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K + channels activator with an EC50 of 6.94 μM. QO-40 stimulated Ca 2+-activated K + current (IK(Ca)) with an EC50 value of 2.3 μM in pituitary GH3 lactotrophs .
    QO-40

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