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Pyridoxal isonicotinoyl hydrazone

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114758
    Pyridoxal isonicotinoyl hydrazone
    4 Publications Verification

    		 Biochemical Assay Reagents Ferrochelatase Cardiovascular Disease
    Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., β-thalassemia) .
    Pyridoxal isonicotinoyl hydrazone

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