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Protionamide-d<sub>5</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0306S

    Protionamide-d<sub>5sub>

    Isotope-Labeled Compounds Bacterial Infection
    Prothionamide-d5 is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .
    Prothionamide-d5

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