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Prostaglandin E2 (Standard)

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7

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101952R
    Prostaglandin E2 (Standard)
    40+ Cited Publications

    PGE2(Standard); Dinoprostone (Standard)

    		 Reference Standards Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2 (Standard)
  • HY-135023R
    5-trans-PGE2 (Standard)

    5-trans Prostaglandin E2 (Standard)

    		 Cytochrome P450 Prostaglandin Receptor Reference Standards Cancer
    5-trans-PGE2 (Standard) is the analytical standard of 5-trans-PGE2. This product is intended for research and analytical applications. 5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer .
    5-trans-PGE2 (Standard)
  • HY-N3617R
    Coniferin (Standard)

    Laricin (Standard)

    		 Reference Standards Fungal Infection
    Coniferin (Standard) is an analytical standard for Coniferin. This product is intended for research and analytical applications. Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal melanization. Coniferin inhibits the release of certain hormones from cells, including Prostaglandin E2 and Thromboxane B2 .
    Coniferin (Standard)
  • HY-16781R
    Grapiprant (Standard)

    		Prostaglandin Receptor Metabolic Disease Endocrinology Cancer
    Grapiprant (Standard) is the analytical standard of Grapiprant. This product is intended for research and analytical applications. Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment .
    Grapiprant (Standard)
  • HY-W748591R
    Cannflavin A (Standard)

    		Amyloid-β Apoptosis Reference Standards KMO Neurological Disease Inflammation/Immunology Cancer
    Cannflavin A (Standard) is the analytical standard of Cannflavin A. This product is intended for research and analytical applications. Cannflavin A can be isolated from Cannabis sativa L.. Cannflavin A has anti-cancer, neuroprotective and anti-inflammatory activity. Cannflavin A inhibits Aβ1-42 aggregation. Cannflavin A also inhibits kynurenine-3-monooxygenase (KMO) (IC50 = 29.4 μM). Cannflavin A activates apoptosis via caspase-3 cleavage. Cannflavin A exerts anti-inflammatory effects by inhibiting pro-inflammatory enzymes, including prostaglandin E2 and cytochrome c oxidases I and II in PC12 cell line .
    Cannflavin A (Standard)
  • HY-B2121R
    6-Methoxy-2-naphthoic acid (Standard)

    6-MNA (Standard); Naproxen impurity O (Standard)

    		 Reference Standards Drug Metabolite COX Neurological Disease Inflammation/Immunology
    6-Methoxy-2-naphthoic acid (Standard) (6-MNA (Standard)) is the analytical standard of 6-Methoxy-2-naphthoic acid (HY-B2121). This product is intended for research and analytical applications. 6-Methoxy-2-naphthoic acid (6-MNA) is the active metabolite of Nabumetone (HY-B0559). 6-Methoxy-2-naphthoic acid is also an inhibitor of COX-1 and COX-2. 6-Methoxy-2-naphthoic acid can inhibit the synthesis of gastric mucosal prostaglandin E2. 6-Methoxy-2-naphthoic acid can be used in the research of inflammation and pain-related diseases. In addition, 6-Methoxy-2-naphthoic acid is an impurity in Naproxen (HY-15030) and can also be used in the synthesis of other active compounds.
    6-Methoxy-2-naphthoic acid (Standard)
  • HY-B1311R
    Proadifen hydrochloride (Standard)

    SKF-525A (Standard); U-5446 (Standard); RP-5171 (Standard)

    		 Reference Standards Cytochrome P450 Monoamine Oxidase Bcl-2 Family Survivin PARP Neurological Disease Inflammation/Immunology Cancer
    Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [4] .
    Proadifen hydrochloride (Standard)

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