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Results for "

Polθ inhibitor

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-171421
    Polθ-IN-8

    		DNA/RNA Synthesis Cancer
    Polθ-IN-8 (example 77) is a DNA polymerase theta (Polθ) inhibitor with an c of <100 nM for Polθ ATPase activity. Polθ-IN-8 can be used to study diseases related to Polθ activity (such as cancer) .
    Polθ-IN-8
  • HY-150279
    PolQi2
    2 Publications Verification

    		 DNA/RNA Synthesis Others
    PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research .
    PolQi2
  • HY-169284
    Polθ-IN-5

    		DNA/RNA Synthesis Cancer
    Polθ-IN-5 (Compound 139) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-5 has antitumor activity .
    Polθ-IN-5
  • HY-153755
    Polθ-IN-7

    		DNA/RNA Synthesis Cancer
    Polθ-IN-7 (example 12) is a DNA polymerase theta (Polθ) inhibitor with a Ki of 1.27 nM .
    Polθ-IN-7
  • HY-169285
    Polθ-IN-6

    		DNA/RNA Synthesis Cancer
    Polθ-IN-6 (Compound 89) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-6 has antitumor activity .
    Polθ-IN-6

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