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Pks13-IN-1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170575
    Pks13-IN-1

    		Bacterial Infection
    Pks13-IN-1 (Compound 44) is an orally active inhibitor for Mycobacterium tuberculosis Polyketide synthase 13 (Pks13). Pks13-IN-1 inhibits M. tuberculosis strain H37Rv with a MIC of 0.07 μM. Pks13-IN-1 exhibits antibacterial efficacy in mouse model .
    Pks13-IN-1
  • HY-172298
    (R,S,S,S)-Orlistat

    (R,S,S,S)-TetrahydrolipstatIN; (R,S,S,S)-Ro-18-0647

    		 Fatty Acid Synthase (FASN) Infection
    (R,S,S,S)-Orlistat is a stereogenic derivative of orlistat (tetrahydrolipstatin; THL) (HY-B0218). (R,S,S,S)-Orlistat inhibits three Mycobacterium tuberculosis lipid esterases, Ag85C (KI: 16.43 μM), Rv3802 (EC50: 16.2 nM), and Pks13-TE .
    (R,S,S,S)-Orlistat

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