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Perfluorotetradecanoic acid

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W073128
    Perfluorotetradecanoic acid

    PFTeDA

    		 PPAR Apoptosis Endocrinology
    Perfluorotetradecanoic acid (PFTeDA) is a PPARγ inhibitor. Perfluorotetradecanoic acid binds to human PPARγ ligand binding domain with IC50 of 22.8 μM, Kd of 157.8 μM. Perfluorotetradecanoic acid inhibits the function of Leydig cells by inducing oxidative stress and apoptosis. Perfluorotetradecanoic acid stimulates corticosterone biosynthesis but inhibits aldosterone production .
    Perfluorotetradecanoic acid

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