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PRMT7-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173557
    PRMT7-IN-2

    		Histone Methyltransferase Apoptosis Cancer
    PRMT7-IN-2 (A33) is a selective PRMT7 inhibitor with an IC50 of 0.50 μM. PRMT7-IN-2 arrests cell cycle at G0/G1 phase, induces cell apoptosis, and inhibits cell growth in vivo and in vitro. PRMT7-IN-2 decreases the monomethylarginine level of PRMT7, increases expression of epithelial marker (E-cadherin, and reduces expression of mesenchymal markers such as N-cadherin, Vimentin, and ZEB2 .
    PRMT7-IN-2

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