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PPARγ agonist19

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176214
    PPARγ agonist 19

    		PPAR COX Metabolic Disease
    PPARγ agonist 19 (Compound 5e) is a PPARγ agonist. PPARγ agonist 19 has an IC50 of 11.27 μM against COX-1 and an IC50 of 0.05 μM against COX-1. PPARγ agonist 19 increases glucose uptake in rat hemidiaphragm assay and is superior to pioglitazone (HY-13956). PPARγ agonist 19 alleviates hyperglycemia and insulin resistance in an in vivo model of type 2 diabetes in rats and protects against renal and lipidemia damage caused by metabolic dysfunction .
    PPARγ agonist 19

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