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Results for "

PMO

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Peptides

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W357202
    7’-OH-N-trityl morpholinothymine

    PMO Thymidine Precusor

    		 Nucleoside Antimetabolite/Analog Cancer
    7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    7’-OH-N-trityl morpholinothymine
  • HY-132611
    Golodirsen

    SRP-4053

    		 Dystrophin Neurological Disease
    Golodirsen (SRP-4053) is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen can restore the expression of the anti-myostatin protein. Golodirsen can be used for the research of duchenne muscular dystrophy (DMD) .
    Golodirsen
  • HY-132611A
    Golodirsen sodium

    SRP-4053 sodium

    		 DNA/RNA Synthesis Dystrophin Neurological Disease
    Golodirsen (SRP-4053) sodium is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen sodium restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen sodium can restore the expression of the anti-myostatin protein. Golodirsen sodium can be used for the research of duchenne muscular dystrophy (DMD) .
    Golodirsen sodium
  • HY-P10559A
    (RXR)4XB TFA

    		Bacterial Infection
    (RXR)4XB TFA is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB TFA-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .
    (RXR)4XB TFA
  • HY-W893751
    PMO-G

    		Biochemical Assay Reagents Metabolic Disease
    PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy .
    PMO-G
  • HY-P10559
    (RXR)4XB

    		Bacterial Infection
    (RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .
    (RXR)4XB

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