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Pathways Recommended:	PI3K/Akt/mTOR

Results for "

PI3K/Akt/mTOR-IN-4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) mTOR (2) PI3K (2) Apoptosis (2) Drug Intermediate (1) Microtubule/Tubulin (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (2) Endocrinology (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Targets Recommended: Akt mTOR PI3K Dan family AIM2 NEKs CD44

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W004121

4-Biphenylsulfonyl chloride	Drug Intermediate	Cancer
4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the *PI3K/Akt/mTOR* pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .

HY-106591A

4-Vinylcyclohexene dioxide VINylcyclohexene diepoxide	Apoptosis Reactive Oxygen Species (ROS) PI3K Akt mTOR	Endocrinology
4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the *PI3K/Akt/mTOR* pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .

HY-163511

*PI3K/Akt/mTOR-IN-4*	Akt Apoptosis mTOR PI3K Microtubule/Tubulin	Cancer
PI3K/Akt/mTOR-IN-4 (compound 4r) is a potent *PI3K/Akt/mTOR* and tubulin polymerization inhibitor. PI3K/Akt/mTOR-IN-4 induce apoptosis and cell cycle arrest at G2/M phase. PI3K/Akt/mTOR-IN-4 decreases the expression of p-PI3K, p-Akt, and p-mTOR, β-tubulin .

Cat. No.	Product Name	Type

HY-W004121

4-Biphenylsulfonyl chloride	Biochemical Assay Reagents
4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the *PI3K/Akt/mTOR* pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .

4-Biphenylsulfonyl chloride

Biochemical Assay Reagents

4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .

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