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Pathways Recommended: PI3K/Akt/mTOR
Results for "

PI3K/Akt/CREB axis

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18939
    N6-Cyclohexyladenosine
    2 Publications Verification

    CHA

    		 Adenosine Receptor PI3K Akt Epigenetic Reader Domain Neurological Disease Cancer
    N6-Cyclohexyladenosine is a selective adenosine A1 receptor agonist (EC50 = 8.2 nM). N6-Cyclohexyladenosine enhances the activation of the PI3K/Akt/CREB/BDNF axis. N6-Cyclohexyladenosine promotes remyelination, induces sleep, and improves 3-NP-induced Huntington's disease. N6-Cyclohexyladenosine can be used in liver cancer research .
    N6-Cyclohexyladenosine
  • HY-155520
    Antileishmanial agent-19

    		Parasite Infection
    Antileishmanial agent-19 (Compound F27) is an antileishmanial agent, with a IC50 of 3.39 μM for L. donovani promastigotes. Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase. Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes. Antileishmanial agent-19 reduces parasite burden in L.d-infected animals .
    Antileishmanial agent-19

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