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PCB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Drug Derivative (1) Isotope-Labeled Compounds (4) Potassium Channel (4) Pyroptosis (2) Reactive Oxygen Species (ROS) (1) Reference Standards (2) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Endocrinology (1) Metabolic Disease (1) Neurological Disease (6)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-117532

PenCB PCB 118	Pyroptosis	Cancer
PenCB (PCB 118) could induces pyroptosis by priming and activating NFκB-dependent NLRP3 inflammasome. PCB 118 induces oxidative stress and pyroptosis are dependent on Aryl hydrocarbon receptor (AhR) activation and subsequent cytochrome P450 1A1 upregulation .

HY-14946

Amifampridine 3,4-Diaminopyridine	Potassium Channel	Neurological Disease
Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-W748332

PCB118-13C12 CDE-99-¹³C₁₂; PCB No 118-¹³C₁₂; 2,3',4,4',5-Pentachlorobiphenyl-¹³C₁₂	Isotope-Labeled Compounds	Others
PCB118- ¹³C₁₂ (CDE-99- ¹³C₁₂; PCB No 118- ¹³C₁₂; 2,3',4,4',5-Pentachlorobiphenyl- ¹³C₁₂) is ¹³C labeled PCB118 .

HY-W748319

K 101-13C12 CB 101-¹³C₁₂; PCB 101-¹³C₁₂; 2,2',4,5,5'-Pentachlorobiphenyl-¹³C₁₂	Isotope-Labeled Compounds	Others
K 101- ¹³C₁₂ is ¹³C labeled K 101 .

HY-NP171

DSPE-PCB	Biochemical Assay Reagents	Cardiovascular Disease
DSPE-PCB is a lipid mixture that combines the properties of DSPE and zwitterionic polycarboxybetaine (PCB) and can be used for liposome preparation .

HY-128431

Arochlor 1254	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation .

HY-RS10111

PC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PC Human Pre-designed siRNA Set A contains three designed siRNAs for PC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PC Human Pre-designed siRNA Set A PC Human Pre-designed siRNA Set A

HY-117532R

PenCB (Standard)	Pyroptosis	Cancer
PenCB (Standard) is the analytical standard of PenCB. This product is intended for research and analytical applications. PenCB (PCB 118) could induces pyroptosis by priming and activating NFκB-dependent NLRP3 inflammasome. PCB 118 induces oxidative stress and pyroptosis are dependent on Aryl hydrocarbon receptor (AhR) activation and subsequent cytochrome P450 1A1 upregulation .

HY-W673588

2,3-Dichlorobiphenyl	Drug Derivative	Endocrinology
2,3-Dichlorobiphenyl is a polychlorinated biphenyl (PCB). 2,3-Dichlorobiphenyl is an endocrine disruptor that affects gonadal differentiation in Xenopus laevis .

HY-14946A

Amifampridine phosphate 3,4-Diaminopyridine phosphate	Potassium Channel	Neurological Disease
Amifampridine (3,4-Diaminopyridine) phosphate is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine phosphate is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine phosphate increases transmitter release from neuromuscular junctions (NMJs). Amifampridine phosphate can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-176305S

Neurofilament, U-15N	Isotope-Labeled Compounds	Neurological Disease
Neurofilament, U- ¹⁵N is the ¹⁵N-labeled Neurofilament.

HY-W002097R

1-(5-Methylthiophen-2-yl)ethan-1-one (Standard) 2-Acetyl-5-methylthiophene (Standard)	Reference Standards Others	Others
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-14946R

Amifampridine (Standard) 3,4-Diaminopyridine (Standard)	Reference Standards Potassium Channel	Neurological Disease
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-14946S

Amifampridine-d3 3,4-Diaminopyridine-d₃	Isotope-Labeled Compounds Potassium Channel	Neurological Disease
Amifampridine-d₃ (3,4-Diaminopyridine-d₃) is deuterium labeled Amifampridine. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Cat. No.	Product Name	Type

HY-NP171

DSPE-PCB	Drug Delivery
DSPE-PCB is a lipid mixture that combines the properties of DSPE and zwitterionic polycarboxybetaine (PCB) and can be used for liposome preparation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W002097R

1-(5-Methylthiophen-2-yl)ethan-1-one (Standard) 2-Acetyl-5-methylthiophene (Standard)	Structural Classification Natural Products Source classification Rubiaceae Plants Coffea arabica L.	Reference Standards Others
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Species:	Rat (1) Mouse (2)
Tag:	His (3)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71925A

	SCGB1A1 Protein, Rat (His) Scgb1a1; Cc10; Ugb; UtgUteroglobin; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1	Rat	E. coli
	SCGB1A1 Protein demonstrates diverse binding abilities, interacting with phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB), and, to a lesser extent, progesterone.It acts as a robust phospholipase A2 inhibitor, forming an antiparallel homodimer linked by disulfide bonds.Although there is controversy regarding its interaction with LMBR1L, additional research is necessary for clarification.SCGB1A1 Protein, Rat (His) is the recombinant rat-derived SCGB1A1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P71936A

	SCGB1A1 Protein, Mouse (His) Scgb1a1; Cc10; Ugb; Utg; Uteroglobin; Clara cell 17 kDa protein; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1	Mouse	E. coli
	Uteroglobin/SCGB1A1 protein has multiple binding abilities and can interact with phosphatidylcholine, phosphatidylinositol, PCB, and binds weakly to progesterone.As a potent phospholipase A2 inhibitor, its antiparallel homodimer structure is maintained by disulfide bonds.SCGB1A1 Protein, Mouse (His) is the recombinant mouse-derived SCGB1A1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P71419

	Uteroglobin/SCGB1A1 Protein, Mouse (HEK293, His) Uteroglobin; Clara cell 17 kDa protein; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1; Scgb1a1; Cc10; Ugb; Utg	Mouse	HEK293
	Uteroglobin/SCGB1A1 protein has multiple binding abilities and can interact with phosphatidylcholine, phosphatidylinositol, PCB, and binds weakly to progesterone.As a potent phospholipase A2 inhibitor, its antiparallel homodimer structure is maintained by disulfide bonds.Uteroglobin/SCGB1A1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Uteroglobin/SCGB1A1 protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W748332

PCB118-13C12
PCB118- ¹³C₁₂ (CDE-99- ¹³C₁₂; PCB No 118- ¹³C₁₂; 2,3',4,4',5-Pentachlorobiphenyl- ¹³C₁₂) is ¹³C labeled PCB118 .

HY-W748319

K 101-13C12
K 101- ¹³C₁₂ is ¹³C labeled K 101 .

HY-176305S

Neurofilament, U-15N
Neurofilament, U- ¹⁵N is the ¹⁵N-labeled Neurofilament.

HY-14946S

Amifampridine-d3
Amifampridine-d₃ (3,4-Diaminopyridine-d₃) is deuterium labeled Amifampridine. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Amifampridine-d3

Amifampridine-d₃ (3,4-Diaminopyridine-d₃) is deuterium labeled Amifampridine. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82315

	PCB Antibody (YA2060) PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB	WB, ICC/IF	Human, Mouse, Rat
	PCB Antibody (YA2060) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2060), targeting PCB, with a predicted molecular weight of 130 kDa (observed band size: 130 kDa). PCB Antibody (YA2060) can be used for WB, ICC/IF experiment in human, mouse, rat background.