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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

Results for "

Nuclear factor-kappaB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NF-κB (3) Apoptosis (2) Calcineurin (1) Caspase (1) Isotope-Labeled Compounds (1) mRNA (1) RANKL/RANK (2) TNF Receptor (1)
By Research Areas:	Cancer (3) Endocrinology (2) Infection (1) Inflammation/Immunology (3) Neurological Disease (2)
Oligonucleotides:	mRNA (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: NF-κB Orphan Nuclear Receptor Nuclear Factor of activated T Cells (NFAT) Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9958

Denosumab 1 Publications Verification AMG-162	NF-κB Caspase Apoptosis RANKL/RANK	Endocrinology Cancer
Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the *receptor activator of nuclear* factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (K_D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB** pathway. Denosumab can be used in bone-related studies .

HY-P9958A

Denosumab (anti-TNFSF11) 1 Publications Verification	RANKL/RANK Apoptosis NF-κB	Neurological Disease Endocrinology Cancer
Denosumab (anti-TNFSF11) is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the *receptor activator of nuclear* factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (K_D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB** pathway. Denosumab can be used in bone-related studies .

HY-138063

Siegeskaurolic acid	TNF Receptor NF-κB	Inflammation/Immunology
Siegeskaurolic acid is an orally active anti-inflammatory agent. Siegeskaurolic acid inhibits the productions of nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha) and the activationon of nuclear factor-kappaB .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-174568

Human NFKB2 mRNA	mRNA	Inflammation/Immunology
Human NFKB2 mRNA encodes the human nuclear factor kappa B subunit 2 (NFKB2) protein, a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. NFKB2 can function as either a transcriptional activator or repressor depending on its dimerization partner.

HY-N9736

6,4'-Dihydroxy-7-methoxyflavanone	Calcineurin	Infection Neurological Disease Inflammation/Immunology
6,4'-Dihydroxy-7-methoxyflavanone, a flavonoid, is a nature product that could be isolated from Heartwood Dalbergia odorifera. 6,4'-Dihydroxy-7-methoxyflavanone inhibits receptor activators of nuclear factor kappa-B ligand (RANKL) induced osteoclastogenesis. 6,4'-Dihydroxy-7-methoxyflavanone has antioxidant, anti-inflammatory and neuroprotective effects. 6,4'-Dihydroxy-7-methoxyflavanone can be used in research of osteoporosis .

Cat. No.	Product Name	Target	Research Area

HY-P9958

Denosumab 1 Publications Verification AMG-162	NF-κB Caspase Apoptosis RANKL/RANK	Endocrinology Cancer
Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the *receptor activator of nuclear* factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (K_D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB** pathway. Denosumab can be used in bone-related studies .

HY-P9958A

Denosumab (anti-TNFSF11) 1 Publications Verification	RANKL/RANK Apoptosis NF-κB	Neurological Disease Endocrinology Cancer
Denosumab (anti-TNFSF11) is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the *receptor activator of nuclear* factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (K_D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB** pathway. Denosumab can be used in bone-related studies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-138063

Siegeskaurolic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Compositae Tephrosia candida DC.	TNF Receptor NF-κB
Siegeskaurolic acid is an orally active anti-inflammatory agent. Siegeskaurolic acid inhibits the productions of nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha) and the activationon of nuclear factor-kappaB .

HY-N9736

6,4'-Dihydroxy-7-methoxyflavanone	Structural Classification Flavonoids Dalbergia odorifera T. Chen Flavones Leguminosae Source classification Plants	Calcineurin
6,4'-Dihydroxy-7-methoxyflavanone, a flavonoid, is a nature product that could be isolated from Heartwood Dalbergia odorifera. 6,4'-Dihydroxy-7-methoxyflavanone inhibits receptor activators of nuclear factor kappa-B ligand (RANKL) induced osteoclastogenesis. 6,4'-Dihydroxy-7-methoxyflavanone has antioxidant, anti-inflammatory and neuroprotective effects. 6,4'-Dihydroxy-7-methoxyflavanone can be used in research of osteoporosis .

Species:	Human (2)
Tag:	GST (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P701788

	IKKε Protein, Human (sf9, GST) IKKε; Inhibitor of Nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	Human	Sf9 insect cells
	IKKε protein is a serine/threonine kinase that coordinates the inflammatory response to viral infection by activating type I IFN, NF-kappa-B, and STAT signaling pathways. Upon activation of the viral RNA sensor, IKKε binds to DDX3X and phosphorylates IRF3, IRF7, and DDX3X, resulting in IRF3 nuclear translocation. IKKε Protein, Human (sf9, GST) is the recombinant human-derived IKKε protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P701786

	IKKβ Protein, Human (sf9, GST) IKBKβ; Inhibitor of Nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB	Human	Sf9 insect cells
	IKKβ protein is a serine kinase that is critical in the NF-kappa-B signaling pathway and can respond to various stimuli such as cytokines or cellular stress. As part of the classical IKK complex, IKKβ activates NF-kappa-B through phosphorylation inhibitors, leading to its degradation and release of NF-kappa-B for gene transcription. IKKβ Protein, Human (sf9, GST) is the recombinant human-derived IKKβ protein, expressed by sf9 insect cells , with N-GST labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80719

	IKK beta Antibody (YA347) IKBKB; IKKB; Inhibitor of Nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB	WB, ICC/IF	Human, Mouse, Rat
	IKK beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 87 kDa, targeting to IKK beta. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P82126

	IKK alpha/beta Antibody (YA1871) CHUK; IKKA; TCF16; Inhibitor of Nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B	WB, ICC/IF, IP	Human, Mouse, Rat
	IKK alpha/beta Antibody (YA1871) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1871), targeting IKK alpha/beta, with a predicted molecular weight of 85 kDa (observed band size: 75,87 kDa). IKK alpha/beta Antibody (YA1871) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P85217

	IKK beta Antibody (YA4909) IKBKB; IKKB; Inhibitor of Nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB	WB, IHC-P, ICC/IF, ELISA	Human
	IKK beta Antibody (YA4909) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IKBKB. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

HY-P85216

	IKK alpha Antibody (YA4908) CHUK; IKKA; TCF16; Inhibitor of Nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B	WB, ICC/IF, FC, ELISA	Human
	IKK alpha Antibody (YA4908) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IKKα. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human.

HY-P86384

	IKK alpha Antibody (YA6076) CHUK; IKKA; TCF16; Inhibitor of Nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	IKK alpha Antibody (YA6076) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IKKα. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P81866

	IKK epsilon Antibody (YA1611) IKBKE; IKKE; IKKI; KIAA0151; Inhibitor of Nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	WB, IHC-P, ICC/IF, FC	Human
	IKK epsilon Antibody (YA1611) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1611), targeting IKK epsilon, with a predicted molecular weight of 80 kDa (observed band size: 80 kDa). IKK epsilon Antibody (YA1611) can be used for WB, IHC-P, ICC/IF, FC experiment in human background.

HY-P85218

	IKK epsilon Antibody (YA4910) IKBKE; IKKE; IKKI; KIAA0151; Inhibitor of Nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	WB, ELISA	Human
	IKK epsilon Antibody (YA4910) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IKKε. It can be applicated for WB, ELISA assays, in the background of human.

HY-P86459

	IKK alpha/beta Antibody (YA6151) CHUK; IKKA; TCF16; Inhibitor of Nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	IKK alpha/beta Antibody (YA6151) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IKK alpha/beta.

HY-P85639

	NF-KB p105/p50 Antibody (YA5331) DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappaB; NF kappaBeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor kappa-B, subunit 1; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98.	WB	Human
	NF-KB p105/p50 Antibody (YA5331) is a mouse-derived and non-conjugated monoclonal antibody, targeting to NFKB1. It can be applicated for WB assays, in the background of human.

HY-P85530

	IKK beta Antibody (YA5222) I kappa B kinase 2; I kappa B kinase beta; I-kappa-B kinase 2; I-kappa-B-kinase beta; IkBKB; IKK 2; IKK B; IKK beta; IKK-B; IKK-beta; IKK2; IKKB; IKKB_HUMAN; IMD15; Inhibitor of kappa light chain gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta; Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta; Inhibitor of Nuclear factor kappa B kinase beta subunit; Inhibitor of Nuclear factor kappa B kinase subunit beta; Inhibitor of Nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; Nuclear factor NF kappa B inhibitor kinase beta; Nuclear factor NF-kappa-B inhibitor kinase beta; Nuclear factor of kappa light chain gene enhancer in B cells inhibitor.	WB	Human, Rat
	IKK beta Antibody (YA5222) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IKKβ. It can be applicated for WB assays, in the background of human, rat.

HY-P80244

	NF-KB p105/p50 Antibody (YA699) DKFZp686C01211 antibody; DNA binding factor KBF1 antibody; DNA binding factor KBF1 EBP1 antibody; DNA-binding factor KBF1 antibody; EBP 1 antibody; EBP-1 antibody; EBP1 antibody; KBF1 antibody; MGC54151 antibody; NF kappa B antibody; NF kappaB antibody; NF kappaBeta antibody; NF kB1 antibody; NFkappaB antibody; NFKB 1 antibody; NFKB p105 antibody; NFKB p50 antibody; Nfkb1 antibody; NFKB1_HUMAN antibody; Nuclear factor kappa B DNA binding subunit antibody; Nuclear factor kappa-B, subunit 1 antibody; Nuclear factor NF kappa B p105 subunit antibody; Nuclear factor NF kappa B p50 subunit antibody; Nuclear factor NF-kappa-B p50 subunit antibody; Nuclear factor of kappa light chain gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody; p105 antibody; p50 antibody; p84/NF-kappa-B1 p98 antibody; Transcription factor NFKB1 antibody	WB, ICC/IF, IHC-P	Human, Mouse
	NF-κB p105/p50 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 50 kDa, targeting to NF-κB p105/p50. It can be used for WB,ICC,IHC-P assays with tag free, in the background of Human, Mouse.

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Cat. No.	Product Name		Classification

HY-174568

Human NFKB2 mRNA		mRNA
Human NFKB2 mRNA encodes the human nuclear factor kappa B subunit 2 (NFKB2) protein, a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. NFKB2 can function as either a transcriptional activator or repressor depending on its dimerization partner.

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Nuclear factor-kappaB

Inhibitors & Agonists

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Natural
Products