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Niraparib-d<sub>5</sub>

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W759435
    Niraparib-d5

    MK-4827-d<sub>5sub>

    		 Isotope-Labeled Compounds Apoptosis PARP Cancer
    Niraparib-d5 (MK-4827-d5) is the deuterium labeled Niraparib (HY-10619). Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity .
    Niraparib-d5

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