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Results for "

Nicotiana

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

15

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8723
    (1′S,2′S)-Nicotine-1'-oxide

    		Others Neurological Disease
    (1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum .
    (1′S,2′S)-Nicotine-1'-oxide
  • HY-118614
    β-Nicotyrine

    		Drug Metabolite Neurological Disease
    β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
    β-Nicotyrine
  • HY-N6085
    N-​Caffeoylputrescine,​(E)​-

    		Others Others
    N-​Caffeoylputrescine,​(E)​- is a caffeic acid amide found in the tobacco plants (Nicotiana tabacum L.) .
    N-​Caffeoylputrescine,​(E)​-
  • HY-121858
    Nicotianamine

    		Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Nicotianamine can be isolated from the leaves of Nicotiana Tabacum L.. Nicotianamine is a key biosynthetic precursor of phytosiderophores. Nicotianamine is an iron chelating agent and can promote the transport of iron. Nicotianamine is an angiotensin-converting enzyme (ACE) inhibitor with IC50 values of 76 nM and 59 nM for rhACE2 and rhACE, respectively. Nicotianamine is vital in metal nutrition and metal homeostasis of flowering plants .
    Nicotianamine
  • HY-N3890
    Exoticin

    		Others Others
    Exoticin is a natural product that can be isolated from the leaves of Nicotiana plumbaginifolia .
    Exoticin
  • HY-N15133
    Solanacol

    (-)-Solanacol

    		 Others Others
    Solanacol ((-)-Solanacol) is a plant hormone that can be isolated from tobacco (Nicotiana tabacum L.). Solanacol is the germination stimulants for parasitic plants .
    Solanacol
  • HY-W014928
    Anabasine hydrochloride

    (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
    Anabasine hydrochloride
  • HY-118614R
    β-Nicotyrine (Standard)

    		Reference Standards Drug Metabolite Neurological Disease
    β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
    β-Nicotyrine (Standard)
  • HY-N15360
    Isophytyl acetate

    		Herbicide Infection
    Isophytyl acetate is an organic compound found in Nicotiana plumbaginifolia stems. Isophytyl acetate is promising for research of herbicides .
    Isophytyl acetate
  • HY-N10425
    2-Hydroxyalbrassitriol

    		Cholinesterase (ChE) Neurological Disease
    2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC50 of 35.97 μM .
    2-Hydroxyalbrassitriol
  • HY-W653822
    (2'S)-Nicotine 1-oxide

    (2S)-Nicotine 1-N-oxide

    		 Drug Metabolite Others
    (2'S)-Nicotine 1-oxide ((2S)-Nicotine 1-N-oxide) is an alkaloid N-oxide, which is found in leaves, stems and roots of Nicotiana tabacum .
    (2'S)-Nicotine 1-oxide
  • HY-162417
    PPO-IN-12

    		Herbicide Others
    PPO-IN-12 (Compound E-Ic) an inhibitor for nicotiana tabacum protoporphyrinogen IX oxidase (NtPPO), with the Ki of 3 nM. Antibacterial agent 208 exhibits a board herbicide spectrum, with good inhibitory activity against broadleaf weeds .
    PPO-IN-12
  • HY-159488
    PPO-IN-14

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-14 (compound B11) is a Nicotiana tobacco Protoporphyrinogen oxidase (NtPPO) inhibitor, with a Ki value of 9.05 nM. PPO-IN-14 (compound B11) could help control weeds in agricultural production .
    PPO-IN-14
  • HY-173015
    PPO-IN-16

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-16 (Compound D5) is a PPO inhibitor and herbicide with a Ki of 33.7 nM against Nicotiana tabacum PPO (NtPPO). PPO-IN-16 has a broad herbicidal spectrum and exhibits good safety on crops such as wheat, rice, and peanut .
    PPO-IN-16
  • HY-N7400
    Phaseoloidin

    		Complement System Others
    Phaseoloidin is a homogentisic acid glucoside from Nicotiana attenuata trichomes and contributes to the plant's resistance against lepidopteran herbivores. Phaseoloidin reduces larval growth of the specialist larvae Manduca sexta and the generalist larvae Spodoptera littoralis . Phaseoloidin has anti-complement activitie .
    Phaseoloidin
  • HY-164510
    N-Formyldemecolcine

    		Cytochrome P450 Others
    N-Formyldemecolcine is a colchicine precursor that contains the characteristic tropolone ring and pharmacophore of colchicine. N-Formyldemecolcine can be synthesized de novo by genetically engineering transgenic Nicotiana benthamiana and atypical cytochrome P450s that catalyze the production of colchicine's unique carbon scaffold .
    N-Formyldemecolcine
  • HY-N6740R
    Beta-Zearalanol (Standard)

    		Reference Standards Apoptosis Metabolic Disease
    (±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine. This product is intended for research and analytical applications. (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health .
    Beta-Zearalanol (Standard)
  • HY-N4283
    Coniferyl alcohol

    		Drug Intermediate Fungal Infection Cardiovascular Disease Inflammation/Immunology
    Coniferyl alcohol is an orally active lignin biosynthesis intermediate and antifungal agent. Coniferyl alcohol specifically inhibits the growth of fungi (Verticillium longisporum). Coniferyl alcohol inhibits the growth of Nicotiana benthamiana seedlings. Coniferyl alcohol improves cardiac dysfunction in renovascular hypertension and cardiac inflammation .
    Coniferyl alcohol
  • HY-B1532
    Anabasine

    (S)-Anabasine; (+)-Anabasine

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine
  • HY-N8459
    α-Cembrenediol

    α-CBD

    		 EBV Cancer
    α-Cembrenediol is a potent inhibitor of EBV.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity .
    α-Cembrenediol
  • HY-173058
    NtPPO-IN-1

    		Herbicide Protoporphyrinogen IX oxidase Others
    NtPPO-IN-1 (Compound A4) is the inhibitor for Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. NtPPO-IN-1 exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti and Portulaca oleracea, and exhibits 30-50% injury to corn and rice (150 g a.i./ha) .
    NtPPO-IN-1
  • HY-163570
    PPO-IN-11

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-11 (Compound 10bh) is an inhibitor for protoporphyrinogen IX oxidase (PPO), that inhibits nicotiana tabacum PPO (NtPPO) with Ki of 0.0603 μM. PPO-IN-11 exhibits herbicidal activities against dicot weeds Leaf mustard, Chickweed, Chenopodium serotinum and monocot weeds Alopecurus aequalis, Poa annua, and Polypogon fugax with a dose of 150 g a.i./ha .
    PPO-IN-11
  • HY-B1532R
    Anabasine (Standard)

    (S)-Anabasine (Standard); (+)-Anabasine (Standard)

    		 Reference Standards nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-176531
    Antiviral agent 69

    		Others Infection
    Antiviral agent 69 (Compound L2) is a capsid protein residue THR155-targeting inhibitor of phytoviral intercellular traffic. Antiviral agent 69 has an excellent antiviral activity against Potato virus Y (PVY) with an EC50 of 128.10 μg/mL for inactivation effect. Antiviral agent 69 effectively decreases viral accumulation in host plant Nicotiana benthamiana, promising for novel pesticide research and development .
    Antiviral agent 69
  • HY-W002112R
    (±)-Nornicotine (Standard)

    Nornicotine (Standard)

    		 Reference Standards Endogenous Metabolite Drug Metabolite nAChR β-catenin Cardiovascular Disease Neurological Disease
    (±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine (HY-W002112). This product is intended for research and analytical applications. (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
    (±)-Nornicotine (Standard)
  • HY-W002112
    (±)-Nornicotine

    Nornicotine

    		 Endogenous Metabolite Drug Metabolite nAChR β-catenin Cardiovascular Disease Neurological Disease
    (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
    (±)-Nornicotine
  • HY-172151
    PPO-IN-17

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm 2). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm 2) or on honeybees (at a concentration of 6400 mg/kg) .
    PPO-IN-17

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