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Results for "

Nematicidal

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

9

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121325
    Fervenulin

    		Parasite Infection
    Fervenulin has nematicidal activity and inhibits egg hatch and J2 mortality of M. incognita with MICs of 30 μg/mL and 120 μg/mL, respectively .
    Fervenulin
  • HY-N1458
    Isoschaftoside
    1 Publications Verification

    		 Parasite Autophagy p62 Reactive Oxygen Species Infection Metabolic Disease Inflammation/Immunology Cancer
    Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, can inhibit the growth of germinated S. hermonthica radicles. Isoschaftoside reduces reactive oxygen species (ROS) and induces proliferation in senescent cells. Isoschaftoside activates autophagy. Isoschaftoside can be used for anti-tumor, anti-inflammatory, antioxidant, antihypertensive, hepatoprotective and nematicidal study .
    Isoschaftoside
  • HY-P5957
    Omphalotin A

    		Parasite Infection
    Omphalotin A is a cyclic peptide, and shows nematicidal activity .
    Omphalotin A
  • HY-W012941
    2-Thiophenecarboxaldehyde

    Thiophene-2-carboxaldehyde

    		 Antibiotic Bacterial Parasite Infection
    2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities .
    2-Thiophenecarboxaldehyde
  • HY-163780
    AChE-IN-66

    		Parasite Infection
    Nematicidal agent 1 is a potent nematicidal agent. Nematicidal agent 1 binds to the pocket of acetylcholine esterase (AChE) .
    AChE-IN-66
  • HY-N3754
    Dihydropinosylvin monomethyl ether

    		Parasite Infection
    Dihydropinosylvin monomethyl ether is a natrual compound with nematicidal activity. Dihydropinosylvin monomethyl ether can inhibit pine wood nematodes infection .
    Dihydropinosylvin monomethyl ether
  • HY-123897
    Chamaejasmenin C

    		Parasite Infection
    Chamaejasmenin C, a biflavanone, shows nematicidal activity against second-stage juveniles (J2s) of B. xylophilus and B. mucronatus .
    Chamaejasmenin C
  • HY-N1621
    1-Deacetylnimbolinin B

    		Fungal Parasite Infection
    1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties .
    1-Deacetylnimbolinin B
  • HY-N1458R
    Isoschaftoside (Standard)

    		Parasite Autophagy p62 Reactive Oxygen Species Infection Metabolic Disease Inflammation/Immunology Cancer
    Isoschaftoside (Standard) is the analytical standard of Isoschaftoside. This product is intended for research and analytical applications. Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, can inhibit growth of germinated S. hermonthica radicles. Isoschaftoside reduces reactive oxygen species (ROS) and induces proliferation in senescent cells. Isoschaftoside activates autophagy. Isoschaftoside can be used for anti-tumor, anti-inflammatory, antioxidant, antihypertensive, hepatoprotective and nematicidal study.
    Isoschaftoside (Standard)
  • HY-125596
    Lachnumon

    		Parasite Infection
    Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .
    Lachnumon
  • HY-W012941R
    2-Thiophenecarboxaldehyde (Standard)

    Thiophene-2-carboxaldehyde (Standard)

    		 Reference Standards Antibiotic Bacterial Parasite Infection
    2-Thiophenecarboxaldehyde (Standard) is the analytical standard of 2-Thiophenecarboxaldehyde. This product is intended for research and analytical applications. 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities .
    2-Thiophenecarboxaldehyde (Standard)
  • HY-172212
    SDH-IN-23

    		Insecticide Reactive Oxygen Species Infection
    SDH-IN-23 (Compound B21) is an SDH inhibitor. SDH-IN-23 exhibits excellent nematicidal activity. SDH-IN-23 can inhibit the feeding, reproduction, and embryonic development of nematodes. Meanwhile, SDH-IN-23 exerts a lethal effect on nematodes by triggering oxidative stress, causing intestinal damage, and inhibiting SDH, among other mechanisms .
    SDH-IN-23
  • HY-116090
    Conoidin A

    		Parasite Infection Cardiovascular Disease Neurological Disease
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease .
    Conoidin A
  • HY-159959
    cis-3-Indoleacrylic acid

    		Proton Pump Others
    cis-3-Indoleacrylic acid is a nematicidal compound that can be isolated from Streptomyces youssoufiensis YMF3.862. cis-3-Indoleacrylic acid is also a V‑ATPase inhibitor, and inhibits V-ATPase expression and enzyme activity. cis-3-Indoleacrylic acid causes Meloidogyne incognita juveniles to have swollen bodies with apparent cracks on the cuticle surface (LC50: 16.31 μg/mL). cis-3-Indoleacrylic acid inhibits H + accumulation in nematode bodies .
    cis-3-Indoleacrylic acid
  • HY-173264
    SDH-IN-24

    		Parasite Insecticide Infection
    SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields .
    SDH-IN-24
  • HY-138074
    Milbemycin A4 oxime

    5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime

    		 Parasite Infection
    Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
    Milbemycin A4 oxime

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