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Results for "

NOG mouse

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Ligands for Target Protein for PROTAC (1) MDM-2/p53 (2) Orphan GPCR (1) PROTACs (1) Sirtuin (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (3) Infection (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

KT-253	PROTACs MDM-2/p53 Apoptosis	Cancer
KT-253 is a p53 stabilizer and a PROTAC degrader for MDM2 (DC₅₀=0.4 nM). KT-253 inhibits the proliferation of cancer cell RS4;11 with an IC₅₀ of 0.3 nM, arrests the cell cycle at G2/M phase, and induces apoptosis. KT-253 exhibits antitumor efficacy in mouse models . (Pink: ligand for target protein MDM2 ligand 4 (HY-170452); Black: linker (HY-W001478); Blue: ligand for E3 ligase cereblon (HY-163927))

Nog Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nog Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nog gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nog Mouse Pre-designed siRNA Set A Nog Mouse Pre-designed siRNA Set A

MDM2 ligand 4	MDM-2/p53 Ligands for Target Protein for PROTAC	Cancer
MDM2 ligand 4 is the ligand for MDM2 that can be used for synthesis of PROTAC degrader KT-253 (HY-170451) .

SAR-446523	Orphan GPCR	Cancer
SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC). SAR-446523 has potent antitumor activity with improvement of mouse survival in NK humanized NOG huIL15 transgenic mice model bearing MM cells. SAR-446523 can be used for multiple myeloma (MM) research .

FLS-359	Sirtuin	Infection
FLS-359 is a selective, orally active allosteric modulator for sirtuin 2, with the IC₅₀ of 3 μM. FLS-359 exhibits antiviral activity against RNA and DNA virus, through inhibition of DNA/RNA replication .

Cat. No.	Product Name	Target	Research Area

SAR-446523	Orphan GPCR	Cancer
SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC). SAR-446523 has potent antitumor activity with improvement of mouse survival in NK humanized NOG huIL15 transgenic mice model bearing MM cells. SAR-446523 can be used for multiple myeloma (MM) research .

Cat. No.	Compare	Product Name	Species	Source

	*Noggin Protein, Mouse* (CHO)** 5+ Cited Publications rMuNOGgin; NOG	Mouse	CHO
	Noggin protein is an important BMP inhibitor that plays an indispensable role in the neural tube, somite growth, cartilage morphogenesis, and joint formation. Its homodimeric structure promotes significant interactions with GDF5 and possibly GDF6, inhibiting chondrocyte differentiation. Noggin Protein, Mouse (CHO) is the recombinant mouse-derived Noggin protein, expressed in CHO.

	*Noggin Protein, Mouse* (HEK293, His)** 2 Publications Verification NOGgin; NOG	Mouse	HEK293
	Noggin is an indispensable factor in cartilage morphogenesis and joint formation, a potent inhibitor of bone morphogenetic protein (BMP) signaling, and plays a crucial role in the growth and patterning of the neural tube and somites.By forming homodimers, Noggin acts as a key regulator to inhibit chondrocyte differentiation by interacting with growth and differentiation factors, particularly GDF5 and possibly GDF6.Noggin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Noggin protein, expressed by HEK293 , with C-6*His labeled tag.

	*Noggin Protein, Mouse* (HEK293)** NOG; NOGgin; SYM1; SYNS1; SYNS1A	Mouse	HEK293
	Noggin is an indispensable factor in cartilage morphogenesis and joint formation, a potent inhibitor of bone morphogenetic protein (BMP) signaling, and plays a crucial role in the growth and patterning of the neural tube and somites.By forming homodimers, Noggin acts as a key regulator to inhibit chondrocyte differentiation by interacting with growth and differentiation factors, particularly GDF5 and possibly GDF6.Noggin Protein, Mouse (HEK293) is the recombinant mouse-derived Noggin protein, expressed by HEK293 , with tag free.

	*Noggin Protein, Mouse* (HEK293, Fc)** NOG; NOGgin; SYM1; SYNS1; SYNS1A	Mouse	HEK293
	Noggin is an indispensable factor in cartilage morphogenesis and joint formation, a potent inhibitor of bone morphogenetic protein (BMP) signaling, and plays a crucial role in the growth and patterning of the neural tube and somites.By forming homodimers, Noggin acts as a key regulator to inhibit chondrocyte differentiation by interacting with growth and differentiation factors, particularly GDF5 and possibly GDF6.Noggin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Noggin protein, expressed by HEK293 , with C-hFc labeled tag.

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Nog Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nog Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nog gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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