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NADase

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2940
    NADase

    		Biochemical Assay Reagents Others
    NADase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    NADase
  • HY-W021879
    DSRM-3716
    5+ Cited Publications

    5-Iodoisoquinoline

    		 Toll-like Receptor (TLR) Neurological Disease
    DSRM-3716 (5-Iodoisoquinoline) is a potent and selective SARM1 NADase inhibitor with an IC50 of 75 nM. DSRM-3716 is selective against other NAD +-processing enzymes, receptors, and transporters. DSRM-3716 provides robust axon protection .
    DSRM-3716
  • HY-134358A
    Ara-F-NAD+ sodium

    		CD38 Neurological Disease
    Ara-F-NAD+ sodium is an arabino analogue of NAD +. Ara-F-NAD+ sodium is a potent, reversible and slow-binding CD38 NADase inhibitor .
    Ara-F-NAD+ sodium
  • HY-134358
    Ara-F-NAD+

    		CD38 Neurological Disease
    Ara-F-NAD+ is an arabino analogue of NAD +. Ara-F-NAD+ is a potent, reversible and slow-binding CD38 NADase inhibitor .
    Ara-F-NAD+
  • HY-175879
    SARM1-IN-7

    		Toll-like Receptor (TLR) Neurological Disease
    SARM1-IN-7 is a potent active site (orthosteric) and orally active SARM1 inhibitor. SARM1-IN-7 continuously activates the enzymatic activity of SARM1, thereby exacerbating the depletion of NAD at sub-minimal concentrations. SARM1-IN-7 demonstrated dual benefits in the SARM1-activated cell models and mouse models: a high dose exerted a cell/neuron protective effect, while a low dose exacerbated cell/neuron damage. SARM1-IN-7 can be used for the study of axon degeneration .
    SARM1-IN-7

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