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Molecular gel

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0021
    Ethidium bromide
    10+ Cited Publications

    EtBr; Homidium bromide

    DNA Stain Others
    Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
    Ethidium bromide
  • HY-156045C

    Biochemical Assay Reagents Others
    Cross-linked dextran G 200 is a hydrophilic gel based on molecular size exclusion and targeted macromolecular separation. Cross-linked dextran G 200 works through the gel permeation mechanism, and the cross-linked structure forms a three-dimensional network with a specific pore size, achieving separation based on the molecular hydrodynamic volume. Cross-linked dextran G 200 can be used to adjust the osmotic solute distribution coefficient and the ability to maintain osmotic equilibrium, such as in gel filtration chromatography for purification and analysis of biomacromolecules such as proteins and nucleic acids . Cross-linked dextran G 200 can also be used as a gel filtration filler (particle size range: 40-120 μm; globular protein separation range: 5-600 kDa) .
    Cross-linked dextran G 200
  • HY-W088070A
    Agarose,Low melting point
    1 Publications Verification

    Biochemical Assay Reagents Others
    Agarose,Low melting point is a kind of agarose, a kind of polysaccharide that can be derived from seaweed. It is commonly used in molecular biology and biochemistry to isolate and purify DNA and RNA fragments. Agarose,Low melting point is a low melting point agarose, which is suitable for the recovery of large DNA fragments and enzymatic reactions in gels and other applications. In addition, it has been used in various techniques, such as pulsed field gel electrophoresis and capillary electrophoresis for analyzing genetic material.
    Agarose,Low melting point
  • HY-W460471

    Biochemical Assay Reagents Others
    Tris Buffered Saline is a common buffer reagent in molecular biology, consisting of Tris and NaCl. Tris Buffered Saline can adjust pH and ionic strength and is widely used in DNA/RNA extraction, PCR and protein electrophoresis. Tris Buffered Saline can purify and protect nucleic acid materials and improve reaction efficiency and concentration. In protein electrophoresis, Tris Buffered Saline stabilizes gels and maintains pH. Overall, Tris Buffered Saline offers versatility, good solubility, and low toxicity in molecular biology applications.
    Tris Buffered Saline
  • HY-Y1309

    Furro ER; NSC 9586; Nako TRB

    Endogenous Metabolite Others
    1-naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media .
    1-Naphthol
  • HY-165517

    Others Cardiovascular Disease
    Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia .
    Methyl acetimidate
  • HY-153802A

    Apoptosis Phosphodiesterase (PDE) Molecular Glues Cancer
    Antitumor agent-100 (compound A6) hydrochloride is an orally potent apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 hydrochloride binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis .
    Antitumor agent-100 hydrochloride
  • HY-153802

    Apoptosis Phosphodiesterase (PDE) Cancer
    Antitumor agent-100 (compound A6) is an orally available apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis .
    Antitumor agent-100
  • HY-Y0850U4

    Polyvinyl alcohol (Mw 145000, 99+% hydrolyzed, ~3300 polymerization); Poly(Ethenol) (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is a polyvinyl alcohol with molecular weight of 145000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)
  • HY-Y0850U8

    Polyvinyl alcohol (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization); Poly(Ethenol) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) is a polyvinyl alcohol with molecular weight of 47000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)
  • HY-Y0850U3

    Polyvinyl alcohol (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization); Poly(Ethenol) (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization) is a polyvinyl alcohol with molecular weight of 125000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization)
  • HY-Y0850U7

    Polyvinyl alcohol (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization); Poly(Ethenol) (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) is a polyvinyl alcohol with molecular weight of 195000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization)
  • HY-Y0850U9

    Polyvinyl alcohol (Mw 67000, 87-89% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 67000, 87-89% hydrolyzed, ~1400 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 67000, 87-89% hydrolyzed, ~1400 polymerization) is a polyvinyl alcohol with molecular weight of 67000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 67000, 87-89% hydrolyzed, ~1400 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 67000, 87-89% hydrolyzed, ~1400 polymerization)
  • HY-170593

    Molecular Glues Metabolic Disease
    ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular gel that can stabilize the interaction of carbohydrate response element binding protein (ChREBP) with 14-3-3 proteins (EC50: 3.8 μM). ChREBPα/14-3-3 regulator-1 effectively protects β cells from glucolipotoxicity and maintains cell function, and can be used in the study of type 2 diabetes .
    ChREBPα/14-3-3 regulator-1
  • HY-Y0850U5

    Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

    Biochemical Assay Reagents Others
    PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a polyvinyl alcohol with molecular weight of 27000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .
    PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)
  • HY-155255

    Ligands for E3 Ligase Cancer
    Thalidomide-5-PEG2-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-PEG2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-PEG2-NH2 hydrochloride
  • HY-156172

    Ligands for E3 Ligase Cancer
    Thalidomide-NH-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-NH-PEG6-NH2 hydrochloride
  • HY-155258

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-PEG7-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-PEG7-NH2 hydrochloride
  • HY-149561

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C4-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C4-NH2 hydrochloride
  • HY-130949B

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C7-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C7-NH2 hydrochloride
  • HY-155266

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C10-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C10-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C10-NH2 hydrochloride
  • HY-149565

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C8-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C8-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C8-NH2 hydrochloride
  • HY-149560

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C3-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C3-NH2 hydrochloride
  • HY-149569

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C12-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C12-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C12-NH2 hydrochloride
  • HY-130965B

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-PEG3-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-PEG3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-PEG3-NH2 hydrochloride
  • HY-153337A

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-C11-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-C11-NH2 hydrochloride
  • HY-155256

    Ligands for E3 Ligase Cancer
    Thalidomide-5-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-PEG6-NH2 hydrochloride
  • HY-149576

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C14-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C14-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C14-NH2 hydrochloride
  • HY-156170

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-5-NH-PEG5-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-NH-PEG5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-NH-PEG5-NH2 hydrochloride
  • HY-155263

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C7-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C7-NH2 hydrochloride
  • HY-155267

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C11-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C11-NH2 hydrochloride
  • HY-155270

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C14-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C14-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C14-NH2 hydrochloride
  • HY-149566

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C9-NH2 hydrochloride
  • HY-156159

    Ligands for E3 Ligase Cancer
    Thalidomide-NH-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-NH-C9-NH2 hydrochloride
  • HY-155268

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C12-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C12-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C12-NH2 hydrochloride
  • HY-156161

    Ligands for E3 Ligase Cancer
    Thalidomide-NH-C13-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C13-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-NH-C13-NH2 hydrochloride
  • HY-149567

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C10-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C10-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C10-NH2 hydrochloride
  • HY-156171

    Ligands for E3 Ligase Cancer
    Thalidomide-5-NH-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-NH-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-NH-PEG6-NH2 hydrochloride
  • HY-155269

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C13-NH2 hydrochloride is a Pomalidomide (HY-10984)-based E3 ubiquitin ligase cereblon (CRBN) ligand for recruiting cereblon proteins. Pomalidomide-5-C13-NH2 hydrochloride can be connected to protein ligands through a linker to form PROTAC.
    Pomalidomide-5-C13-NH2 hydrochloride
  • HY-149564

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C7-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C7-NH2 hydrochloride
  • HY-149574

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C12-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C12-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C12-NH2 hydrochloride
  • HY-149562

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C5-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C5-NH2 hydrochloride
  • HY-149575

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C13-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C13-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C13-NH2 hydrochloride
  • HY-155265

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C9-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C9-NH2 hydrochloride
  • HY-130963B

    E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-4-O-C10-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C10-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C10-NH2 hydrochloride
  • HY-148662

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-PEG5-C2-NH2 hydrochloride
  • HY-155257

    Ligands for E3 Ligase Cancer
    Thalidomide-5-PEG7-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-PEG7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-PEG7-NH2 hydrochloride
  • HY-149571

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C14-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C14-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C14-NH2 hydrochloride
  • HY-149573

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C11-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C11-NH2 hydrochloride
  • HY-149559

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C2-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C2-NH2 hydrochloride

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