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Results for "

Mn2

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Biochemical Assay Reagents

2

Peptides

1

Natural
Products

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132188
    Manganese peroxidase

    		Endogenous Metabolite Others
    Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization [2].
    Manganese peroxidase
  • HY-164220
    PPM1A-IN-1

    		Phosphatase Bacterial Infection
    PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis .
    PPM1A-IN-1
  • HY-P2149
    Concanavalin A
    5 Publications Verification

    		 Antibiotic Apoptosis Infection Inflammation/Immunology Cancer
    Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury .
    Concanavalin A
  • HY-NP164
    Concanavalin A-HRP

    Con A-HRP

    		 Fluorescent Dye Cancer
    Concanavalin A-HRP (Con A-HRP) is a HRP-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-HRP
  • HY-NP164B
    Concanavalin A-AF488

    Con A-AF488

    		 Fluorescent Dye Cancer
    Concanavalin A-AF488 (Con A-AF488) is an AF488-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF488
  • HY-P1188
    LDV-FITC

    		Integrin Cancer
    LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn 2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity [2].
    LDV-FITC
  • HY-W241345
    DOTA-bis(tert-butyl)ester

    		Radionuclide-Drug Conjugates (RDCs) Cancer
    DOTA-bis(tert-butyl)ester is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide conjugates (RDCs). DOTA-bis(tert-butyl)ester can be conjugated with different salts to form different metal chelators, such as (HY-B1244) hydrochloride to obtain DOTA-MN2. DOTA-MN2 can be reacted with [67]Ga-citrate to obtain radiolabeling. When (67)Ga-DOTA-MN2 is incubated in phosphate buffer solution or mouse plasma for 24 hours, it does not undergo significant decomposition. In the biodistribution experiment of NFSa tumor mice, it has high tumor uptake and rapid plasma clearance, and is a good material for SPECT and PET studies.
    DOTA-bis(tert-butyl)ester
  • HY-173084
    BRD6257

    		Phosphatase MDM-2/p53 Cancer
    BRD6257 is an orally active inhibitor for protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D with an IC50 of 5 nM. BRD6257 activates p53 signaling pathway with an EC50 of 51 nM, increases the p21 expression, inhibits the proliferation of cancer cell MOLM13 (IC50=2.8 μM). BRD6257 exhibits good metabolic stability in human and rat liver microsomes .
    BRD6257
  • HY-E70373
    λ Protein phosphatase

    		Biochemical Assay Reagents Others
    λ Protein phosphatase is a serine/threonine phosphatase encoded by bacteriophage Lambda. λ Protein phosphatase is activated with requirement for divalent cations, such as Mn 2+. λ Protein phosphatase is able to dephosphorylate casein, adenovirus E1A protein, and the α subunit of phosphorylase kinase
    λ Protein phosphatase
  • HY-174849
    TdT-IN-1

    		DNA/RNA Synthesis Cancer
    TdT-IN-1 (Compound 8c) is a selective and non-nucleoside terminal deoxynucleotidyl transferase (TdT) inhibitor with IC50 s of 0.11 and 0.19 μM for Mg 2+ and Mn 2+. TdT-IN-1 can be used for leukaemias and skin cancer research .
    TdT-IN-1
  • HY-NP164A
    Concanavalin A-Cy5.5

    Con A-Cy5.5

    		 Fluorescent Dye Cancer
    Concanavalin A-Cy5.5 (Con A-Cy5.5) is a Cy5.5 (HY-D0924)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-Cy5.5
  • HY-P1188A
    LDV-FITC TFA

    		Integrin Cancer
    LDV-FITC TFA, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC TFA binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn 2+ respectively). LDV-FITC TFA can be used to detect α4β1 integrin affinity [2].
    LDV-FITC TFA

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