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Mannitol

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0378
    D-Mannitol
    10+ Cited Publications

    Mannitol; Mannite

    Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol
  • HY-N0378R
    D-Mannitol (Standard)
    10+ Cited Publications

    Mannitol(Standard); Mannite (Standard)

    Reference Standards Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol (Standard) is the analytical standard of D-Mannitol (HY-N0378). This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol (Standard)
  • HY-N0378S1

    Mannitol-13C; Mannite-13C

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol- 13C is the 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-13C
  • HY-N0378S3

    Mannitol-2-13C; Mannite-2-13C

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol-2- 13C is the 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-2-13C
  • HY-P3189

    Biochemical Assay Reagents Others
    Mannitol dehydrogenase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Mannitol dehydrogenase
  • HY-N0378S

    Mannitol-d8; Mannite-d8

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol-d8 is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-d8
  • HY-N0378S4

    Mannitol-d2; Mannite-d2

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol-d2 is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-d2
  • HY-N0378S5

    Mannitol-d1; Mannite-d1

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol-d is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-d1
  • HY-N0378BGL

    Mannitol, M100 (GMP Like); Mannite, M100 (GMP Like)

    Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol, M100 (GMP Like) (Mannitol, M100 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .
    D-Mannitol, M100 (GMP Like)
  • HY-N0378AGL

    Mannitol, M200 (GMP Like); Mannite, M200 (GMP Like)

    Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol, M200 (GMP Like) (Mannitol, M200 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .
    D-Mannitol, M200 (GMP Like)
  • HY-N0378S2

    Mannitol-13C6; Mannite-13C6

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol- 13C6 is the 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-13C6
  • HY-N0378S6

    Mannitol-13C,d2; Mannite-13C,d2

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA Cardiovascular Disease Metabolic Disease Cancer
    D-Mannitol- 13C,d2 is the deuterium and 13C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
    D-Mannitol-13C,d2
  • HY-N6618

    Others Others
    DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone .
    DL-Mannitol
  • HY-N6618S

    Isotope-Labeled Compounds Others
    DL-Mannitol- 13C is the 13C-labeled DL-Mannitol. DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone .
    DL-Mannitol-13C
  • HY-139312S

    Isotope-Labeled Compounds Others
    L-Mannitol-1- 13C is the 13C labeled L-Mannitol. L-mannitol is a compound?can be used for ?the compound sweetener synthesis .
    L-Mannitol-1-13C
  • HY-139312

    Endogenous Metabolite Others
    L-mannitol is a compound can be used for  the compound sweetener synthesis .
    L-Mannitol
  • HY-I0703

    1,2:5,6-Di-O-isopropylidene-D-Mannitol, 97%

    Drug Intermediate Biochemical Assay Reagents Others
    D-Mannitol 1,2:5,6-bis-acetonide is an intermediate.
    Diacetone-D-mannitol, 97%
  • HY-167814

    Biochemical Assay Reagents
    Trimethylsilyl-D-(+)-mannitol is a compound with osmoprotective activity that can effectively scavenge reactive oxygen species (ROS) and provide protection for plants and microorganisms.
    Trimethylsilyl-D-(+)-mannitol
  • HY-W701437

    Biochemical Assay Reagents Others
    1,5-Anhydro-D-mannitol peracetate is a biochemical assay reagent.
    1,5-Anhydro-D-mannitol peracetate
  • HY-W039315

    Biochemical Assay Reagents Others
    2,5-Anhydro-D-mannitol, 97% is a biochemical assay reagent.
    2,5-Anhydro-D-mannitol, 97%
  • HY-44327

    Biochemical Assay Reagents Others
    3,4-O-Isopropylidene-D-mannitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    3,4-O-Isopropylidene-D-mannitol
  • HY-172447

    Antibiotic Bacterial Infection
    1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial effects .
    1,5-Dideoxy-1,5-imino-D-mannitol
  • HY-N9911

    Others Metabolic Disease
    1,5-Anhydro-D-mannitol is the analogue of 1,5-Anhydrosorbitol (HY-113075), and can be used as an experimental control. 1,5-Anhydrosorbitol is a short-term marker for glycemic control.
    1,5-Anhydro-D-mannitol
  • HY-69174

    Bacterial
    1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.
    1-Amino-2,5-anhydro-1-deoxy-D-mannitol
  • HY-13641

    Myelobromol; DBM

    DNA Alkylator/Crosslinker Cancer
    Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia .
    Mitobronitol
  • HY-W552365

    Biochemical Assay Reagents Others
    2,3:5,6-Di-O-isopropylidene-D-mannitol is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    2,3:5,6-Di-O-isopropylidene-D-mannitol
  • HY-W555109

    Biochemical Assay Reagents Others
    1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-mannitol is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    1,6-Dideoxy-1,1-bis(ethylsulfonyl)-L-mannitol
  • HY-W701771

    Biochemical Assay Reagents Others
    D-Mannitol,2,5-anhydro,1,3,4,6-tetraacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    D-Mannitol,2,5-anhydro,1,3,4,6-tetraacetate
  • HY-113024R

    Endogenous Metabolite Reference Standards Metabolic Disease
    D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .
    Pristanic acid (Standard)
  • HY-W009213

    Bis(3-nitrophenyl) disulfide; Nitrophenide

    Parasite Infection
    3-Nitrophenyl disulfide (Bis(3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC50 of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity .
    3-Nitrophenyl disulfide
  • HY-153209

    Biochemical Assay Reagents Others
    Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.
    Adjuvant-4
  • HY-153209G

    Biochemical Assay Reagents Others
    Adjuvant-4 (GMP) is a GMP grade Adjuvant-4. Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.
    Adjuvant-4 (GMP)
  • HY-W436478

    Drug Derivative Others
    (+)-2,5-epi-Goniothalesdiol is an analogue of Goniothalesdiol, which exhibits significant cytotoxicity against P388 mouse leukemia cells and has insecticidal activity. (+)-2,5-epi-Goniothalesdiol can be synthesized starting from D-mannitol (HY-N0378) .
    (+)-2,5-epi-Goniothalesdiol
  • HY-W698627

    Biochemical Assay Reagents Others
    Diethylene glycol monohexyl ether is a biochemical assay reagent.
    2-Deoxy-1,3:4,5-di-O-isopropylidene-2-oxamoylamino-D-mannitol
  • HY-129923

    Cytochrome P450 Neurological Disease
    (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
    (R)-Omeprazole sodium
  • HY-120805

    Antibiotic Others
    Aurofusarin is a secondary metabolite produced by Fusarium graminearum, a widespread pathogen of important crops in temperate climates. F. graminearum also produces monomorphic mannitol, fusarin C, antibiotic Y, 2-amino-14,16-dimethyloctadecane-3-ol (2-AOD-3-ol), aerosporin, and eniacin .
    Aurofusarin
  • HY-134177

    Pyruvate Kinase Metabolic Disease
    2,5-Anhydro-D-glucitol-1,6-diphosphate is a limited stimulator of yeast Pyruvate Kinase. 2,5-Anhydro-D-glucitol-1,6-diphosphate is used as an analogue of the a-form, 2,5-anhydro-D-mannitol 1,6-bisphosphate, while is an excellent allosteric activator of Pyruvate Kinase .
    2,5-Anhydro-D-glucitol-1,6-diphosphate
  • HY-129923R

    HBV Reference Standards Neurological Disease
    (R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
    (R)-Omeprazole sodium (Standard)
  • HY-134338R

    Reference Standards Parasite Others
    (R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
    Ipflufenoquin (Standard)
  • HY-176834

    GLUT Cancer
    3-Deoxy-3-fluoro-D-fructose (Compound 12) is a derivative of 2,5-Anhydro-D-mannitol. 3-Deoxy-3-fluoro-D-fructose is a selective probe of Hexose transporter 5 (GLUT5). 3-Deoxy-3-fluoro-D-fructose inhibits the transport of D-fructose labeled with 14C by GLUT5 with IC50s of 1.16 and 2.37 µM in EMT-6 and MCF-7 cells. 3-Deoxy-3-fluoro-D-fructose can be used for positron emission tomography (PET) imaging of cancers .
    3-Deoxy-3-fluoro-D-fructose

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