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Results for "

MX1

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Natural
Products

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0167
    Gynostemma Extract

    Ginsenoside C-MX1; Gypenoside IX

    		 Endogenous Metabolite Cancer
    Gynostemma Extract (Ginsenoside C-Mx1) is a natural product.
    Gynostemma Extract
  • HY-12098
    Verubulin hydrochloride

    MPC-6827 hydrochloride

    		 Microtubule/Tubulin Cancer
    Verubulin hydrochloride (MPC-6827 hydrochloride) is a blood brain barrier permeable microtubule-disrupting agent, with potent and broad-spectrum in vitro and in vivo cytotoxic activities. Verubulin hydrochloride (MPC-6827 hydrochloride) exhibits potent anticancer activity in human MX-1 breast and other mouse xenograft cancer models. Verubulin hydrochloride (MPC 6827 hydrochloride) is a promising candidate for the treatment of multiple cancer types [1] .
    Verubulin hydrochloride
  • HY-106031
    F-14512

    		Topoisomerase Cancer
    F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC50=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity [1].
    F-14512
  • HY-RS08859
    MX1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MX1 Human Pre-designed siRNA Set A contains three designed siRNAs for MX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MX1 Human Pre-designed siRNA Set A
    MX1 Human Pre-designed siRNA Set A
  • HY-RS24935
    Mx1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Mx1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mx1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Mx1 Rat Pre-designed siRNA Set A
    Mx1 Rat Pre-designed siRNA Set A
  • HY-RS18454
    Mx1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Mx1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mx1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Mx1 Mouse Pre-designed siRNA Set A
    Mx1 Mouse Pre-designed siRNA Set A
  • HY-N14478
    Saframycin Mx1

    		Bacterial Infection
    Saframycin Mx1 has anti-Gram-positive bacteria and Gram-negative bacteria effects [1].
    Saframycin Mx1
  • HY-121372
    Lactandrate

    		Estrogen Receptor/ERR Cancer
    Lactandrate is a D-high nitrogen steroid alkylating agent. It can interact with the ligand-binding domain (LBD) of estrogen receptor-alpha (ERα). Lactandrate has a growth inhibitory effect on breast cancer cells, with a GI50 value ranging from 5 to 65 μM. It shows anti-tumor activity in mouse breast tumors (MXT and CD8F1) as well as in human xenograft MX-1 [1].
    Lactandrate
  • HY-14687
    (rac)-Talazoparib

    (rac)-BMN-673; (rac)-LT-673

    		 PARP Cancer
    (rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is the orally active inhibitor for PARP1/2 with Ki of 1.2 nM and 0.87 nM. (rac)-Talazoparib inhibits cellular PARylation with an EC50 of 2.51 nM. (rac)-Talazoparib causes the accumulation of DNA damage, inhibits proliferation of BRCA1/2-mutated MX-1 cell and Capan-1 cell with IC50 of 0.3 nM and 5 nM. (rac)-Talazoparib exhibits antitumor efficacy in mouse models [1].
    (rac)-Talazoparib
  • HY-155113
    PROTAC Hsp90α degrader 1

    		PROTACs HSP Cancer
    PROTAC Hsp90α degrader 1 (Compound X10g) is a selective PROTAC Hsp90α degrader. PROTAC Hsp90α degrader 1 can be used for breast cancer research. PROTAC Hsp90α degrader 1 inhibits the proliferation of MDA-MB-231, MDA-MB-468, MCF-7, MX-1 cells with IC50s of 51.48 μM, 16.46 μM, 8.93 μM, 11.95 μM respectively [1].
    PROTAC Hsp90α degrader 1
  • HY-123805
    KIN1400

    		HCV IFNAR Infection
    KIN1400 is a potent IRF3 activator. KIN1400 triggers IRF3-dependent innate immune antiviral genes (RIG-I, MDA5, IFIT1, and Mx1) and IFN-β expression. KIN1400 inhibits WNV and DV, two mosquito-borne members of the Flaviviridae and the genus Flavivirus. KIN1400 also inhibits HCV replication. KIN1400 induces innate antiviral immunity through a MAVS-IRF3 axis [1].
    KIN1400

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