MP-2

By Targets:	BRK (1) Interleukin Related (2) Isotope-Labeled Compounds (1) P2Y Receptor (2) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990214

*Anti-Mouse IL-3 Antibody (MP2-8F8)*	Interleukin Related	Others
Anti-Mouse IL-3 Antibody (MP2-8F8) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse IL-3.

HY-122664

XMU-MP-2	BRK	Cancer
XMU-MP-2 is a BRK inhibitor with significant inhibitory activity on BRK-positive cells. XMU-MP-2 inhibits oncogenic BRK-driven tumor growth in a mouse xenograft model. XMU-MP-2 also synergizes with *HER2* inhibitors or endoplasmic reticulum (ER) blockade to exert antiproliferative activity .

HY-P3736

Myelopeptide-2 MP-2	Interleukin Related	Cancer
Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research ^[2].

HY-RS10768

PMP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PMP2 Human Pre-designed siRNA Set A contains three designed siRNAs for PMP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PMP2 Human Pre-designed siRNA Set A PMP2 Human Pre-designed siRNA Set A

HY-167855

MRS4833	P2Y Receptor	Inflammation/Immunology
MRS4833 (compound 15) is an orally active, potent, competitive *P2Y₁₄R* antagonist with an of IC₅₀ of 5.92 nM for *hP2Y₁₄R* and an IC₅₀ of 4.8 nM for *mP2Y₁₄R*. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model .

HY-167855S

1’-Epi Gemcitabine hydrochloride-13C,15N2	Isotope-Labeled Compounds P2Y Receptor	Inflammation/Immunology
1’-Epi Gemcitabine hydrochloride- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled MRS4833 (HY-167855). MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC₅₀ of 5.92 nM for hP2Y14R and an IC₅₀ of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model .

Cat. No.	Product Name	Target	Research Area

HY-P3736

Myelopeptide-2 MP-2	Interleukin Related	Cancer
Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research ^[2].

Cat. No.	Product Name	Target	Research Area

HY-P990214

*Anti-Mouse IL-3 Antibody (MP2-8F8)*	Interleukin Related	Others
Anti-Mouse IL-3 Antibody (MP2-8F8) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse IL-3.

Cat. No.	Product Name	Chemical Structure

HY-167855S

1’-Epi Gemcitabine hydrochloride-13C,15N2
1’-Epi Gemcitabine hydrochloride- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled MRS4833 (HY-167855). MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC₅₀ of 5.92 nM for hP2Y14R and an IC₅₀ of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model .

1’-Epi Gemcitabine hydrochloride-13C,15N2

1’-Epi Gemcitabine hydrochloride- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled MRS4833 (HY-167855). MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC₅₀ of 5.92 nM for hP2Y14R and an IC₅₀ of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83469

	MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; Mitogen activated protein kinase kinase 3; Mitogen activated protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein kinase kinase 2; Stress activated protein kinase kinase 3; Stress-activated protein kinase kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat
	MEK3 Antibody (YA3214) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3214), targeting MEK3, with a predicted molecular weight of 39 kDa (observed band size: 38-40 kDa). MEK3 Antibody (YA3214) can be used for WB, ICC/IF,IP experiment in human, mouse, rat background.

HY-P85516

	MEK1 Antibody (YA5208) AA589381; Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 1; ERK activator kinase 2; FLJ26075; MAP kinase kinase 1; MAP kinase kinase 2; MAP2K1; MAP2K2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK1; MAPKK2; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; Mitogen activated protein kinase kinase 2; Mitogen-activated protein kinase kinase 2, p45; MK2; MKK 1; MKK 2; MKK1; MKK2; MP2K1_HUMAN; PRKMK 1; PRKMK 2; Prkmk1; Prkmk2; protein kinase, mitogen-activated, kinase 1; MAP kinase kinase 1; Protein kinase, mitogen-activated, kinase 1; Protein kinase, mitogen-activated, kinase 2.	WB	Human
	MEK1 Antibody (YA5208) is a mouse-derived and non-conjugated monoclonal antibody, targeting to MEK1. It can be applicated for WB assays, in the background of human.

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Cat. No.	Product Name		Classification

HY-RS10768

PMP2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PMP2 Human Pre-designed siRNA Set A contains three designed siRNAs for PMP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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