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Results for "

MASTL

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Antibodies

1

Click Chemistry

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W231513
    MASTL/Aurora A-IN-1

    		MASTL Ser/Thr Protease Aurora Kinase Cancer
    MASTL/Aurora A-IN-1 (Compound MA4) is a dual inhibitor of MASTL and Aurora A kinases with IC50 values of 0.56 μM and 0.16 μM, respectively. MASTL/Aurora A-IN-1 has broad-spectrum anticancer activity and has potent anticancer activity against SR (leukemia), K-562 (leukemia), MDA-MB-435 (melanoma), MOLT-4 (leukemia), and SK-MEL-2 (melanoma) cell lines in NCI-60 cancer cell lines with GI50 values of 0.023, 0.032, 0.037, 0.044, and 0.051 μM, respectively. MASTL/Aurora A-IN-1 inhibits Aurora A and MASTL kinases, inducing cell cycle G2/M arrest, thereby inhibiting cancer cell proliferation. MASTL/Aurora A-IN-1 can be used in cancer research, especially for tumors with dysregulated mitosis .
    MASTL/Aurora A-IN-1
  • HY-137552
    MKI-1
    1 Publications Verification

    MASTL Kinase Inhibitor-1

    		 MASTL Cancer
    MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer .
    MKI-1
  • HY-156715
    MASTL-IN-1

    		MASTL Cancer
    MASTL-IN-1 is a MASTL (microtubule-associated serine/threonine kinase-like) inhibitor, which is involved in cell proliferation, migration, and invasion. MASTL-IN-1 has potential in cancer research .
    MASTL-IN-1
  • HY-156716
    MASTL-IN-2

    		MASTL Cancer
    MASTL-IN-2 is an MASTL (microtubule-associated serine/threonine kinase-like) inhibitor. MASTL-IN-2 inhibits human epithelial MIA PaCa cancer cell proliferation with IC50 of 2.8 nM .
    MASTL-IN-2
  • HY-RS08165
    MASTL Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MASTL Human Pre-designed siRNA Set A contains three designed siRNAs for MASTL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MASTL Human Pre-designed siRNA Set A
    MASTL Human Pre-designed siRNA Set A
  • HY-RS17985
    Mastl Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mastl Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mastl gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mastl Mouse Pre-designed siRNA Set A
    Mastl Mouse Pre-designed siRNA Set A
  • HY-162731
    MASTL-IN-3

    		MASTL Cancer
    MASTL-IN-3 (compound 60) is a potent MASTL inhibitor with a pIC50 value of 9.10 M. MASTL-IN-3 shows anti-proliferative activity .
    MASTL-IN-3
  • HY-162732
    MASTL-IN-4

    		MASTL Cancer
    MASTL-IN-4(compound 70) is a potent MASTL inhibitor with a pIC50 value of 9.15. MASTL-IN-4 shows anti-proliferative activity .
    MASTL-IN-4
  • HY-159653
    MASTL-IN-5

    		Microtubule/Tubulin Cancer
    MASTL-IN-5 (compound 11) is a MASTL (microtubule-associated serine/threonine kinase-like) inhibitor, with a Ki of 0.018 nM .
    MASTL-IN-5
  • HY-E70743
    MASTL Recombinant Human Active Protein Kinase

    		MASTL Cancer
    MASTL kinase is a master regulator of mitosis, essential for ensuring that mitotic substrate phosphorylation is correctly maintained. It achieves this through the phosphorylation of alpha-endosulfine and subsequent inhibition of the tumor suppressor PP2A-B55 phosphatase. MASTL Recombinant Human Active Protein Kinase is a recombinant MASTL protein that can be used to study MASTL-related functions .
    MASTL Recombinant Human Active Protein Kinase
  • HY-RS24456
    Mastl Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mastl Rat Pre-designed siRNA Set A contains three designed siRNAs for Mastl gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mastl Rat Pre-designed siRNA Set A
    Mastl Rat Pre-designed siRNA Set A

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