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MASP-2-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-172090
    MASP-2-IN-1

    		Ser/Thr Protease Potassium Channel Inflammation/Immunology
    MASP-2-IN-1 (Compound 77) is the inhibitor for mannan-binding lectin-associated serine protease (MASP), that inhibits MASP2 and MASP3 with IC50 of 11.4 nM and 13.2 µM. MASP-2-IN-1 exhibits a weak inhibitory activity against hERG with an IC50 of 175 µM. MASP-2-IN-1 reveals a poor stability in mouse plasma with a half-life of 4.4 hours .
    MASP-2-IN-1

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