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M 36

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Arf Family GTPase (1) PKC (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Targets Recommended: Scavenger Receptor Class B type I (SR-BI）

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

p32 Inhibitor M36 M36	PKC	Cancer
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1 .

Ran-IN-1	Arf Family GTPase Apoptosis	Cancer
Ran-IN-1 (Compound M36) is an orally active and selective Ran GTPase inhibitor. Ran-IN-1 binds to the GDP-bound form of Ran (RanGDP) at the allosteric switch II pocket with high specificity, stabilizing the inactive state and reducing the active Ran-GTP population. Ran-IN-1 induces apoptosis and represses DNA repair pathways like HR and NHEJ in epithelial ovarian cancer (EOC) cells. Ran-IN-1 is promising for research of EOC, particularly high-grade serous carcinoma .

Dusp8 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Dusp8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dusp8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Dusp8 Rat Pre-designed siRNA Set A Dusp8 Rat Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

	*GM-CSF Protein, Feline (M36I, T56A, K126N)* GM-CSF; CSF2; MGC131935; Granulocyte Macrophage Growth Factor	Others	E. coli
	The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Feline (M36I, T56A, K126N) is the recombinant GM-CSF protein, expressed by E. coli , with tag free.

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Dusp8 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Dusp8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dusp8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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