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Results for "

LAG-3-IN-1

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

6

Inhibitory Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162811
    LAG-3 biner 1

    		LAG-3 Cancer
    LAG-3 biner 1 (compound 3) is a small molecule ligand (Kd=1.23 μM) for the immune checkpoint lymphocyte activation gene 3 (LAG-3). LAG-3 biner 1 can be used in the research of cancer diagnosis targeting LAG-3 .
    LAG-3 biner 1
  • HY-P99156
    Relatlimab
    1 Publications Verification

    BMS-986016

    		 LAG-3 Cancer
    Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer .
    Relatlimab
  • HY-P990700
    Tobemstomig

    RO-7247669; RG-6139

    		 PD-1/PD-L1 LAG-3 Inflammation/Immunology
    Tobemstomig is an anti-PDCD1/LAG3 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Tobemstomig
  • HY-P99141
    Anti-Mouse LAG-3 Antibody (C9B7W)

    		LAG-3 Inflammation/Immunology Cancer
    Anti-Mouse LAG-3 Antibody (C9B7W) is an anti-mouse LAG-3 IgG1 monoclonal antibody. Anti-Mouse LAG-3 Antibody (C9B7W) can enhance CD4 + T cell function and exert anti-tumor effects without blocking the interaction between LAG-3 and MHCII. Anti-Mouse LAG-3 Antibody (C9B7W) can be used for research on cancer such as head and neck squamous cell carcinoma (HNSCC) .
    Anti-Mouse LAG-3 Antibody (C9B7W)
  • HY-176814
    LAG-3-IN-1

    		LAG-3 Cancer
    LAG-3-IN-1 (Compound 11) is a LAG-3 inhibitor with a KD of 0.41  μM. LAG-3-IN-1 disrupts the LAG-3/MHCII interaction, enhances IFN-γ secretion and promotes tumor cell killing in cocultures of PBMCs and cancer cells. LAG-3-IN-1 can be used for cancers like ovarian cancer, colon adenocarcinoma and melanoma research .
    LAG-3-IN-1
  • HY-164308
    SA-15-P

    		LAG-3 Inflammation/Immunology
    SA-15-P inhibits LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 values of 4.21 and 6.52 μM respectively. LAG-3/MHCII interaction is a target for immunotherapies .
    SA-15-P
  • HY-P990740
    Fanastomig

    EMB-02; EMB-02

    		 PD-1/PD-L1 LAG-3 Inflammation/Immunology
    Fanastomig is an anti-PDCD1/LAG3 monoclonal antibody .
    Fanastomig
  • HY-P990912
    Cugrastomig

    		LAG-3 Inflammation/Immunology
    HY-P990912 is an PDCD1/LAG3-targeting IgG1κ-[scFv-heavy -κ]2 type chimeric human and humanized antibody .
    Cugrastomig
  • HY-P990204
    Anti-Mouse LAG-3 (D265A) Antibody (C9B7W)

    		LAG-3 Inflammation/Immunology Cancer
    Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) is an anti-mouse LAG-3 IgG1 monoclonal antibody. Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) is a chimeric antibody of the original C9B7W antibody (HY-P99141). Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) contains the D265A mutation region. Anti-Mouse LAG-3 (D265A) Antibody (C9B7W) can be used for research on cancer .
    Anti-Mouse LAG-3 (D265A) Antibody (C9B7W)

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