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Pathways Recommended: Cell Cycle/DNA Damage
Results for "

Krebs cycle

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

5

Biochemical Assay Reagents

7

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-44134

    Dimethyl α-ketoglutarate

    Endogenous Metabolite Autophagy Metabolic Disease
    Dimethyl 2-oxoglutarate (Dimethyl α-ketoglutarate), a cell permeable 2-oxoglutarate derivative, is a tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate serves as a crucial intermediate in the Krebs cycle and an essential nitrogen carrier in metabolic pathways during biological processes. Dimethyl 2-oxoglutarate inhibits autophagy in an IDH1-, IDH2- and ACLY-dependent fashion in cultured human cells. Dimethyl 2-oxoglutarate efficiently prevents autophagy induced by starvation in mice .
    Dimethyl 2-oxoglutarate
  • HY-W013636C
    2-Ketoglutaric acid potassium
    4 Publications Verification

    Alpha-Ketoglutaric acid potassium

    Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Alpha-Ketoglutaric acid) potassium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium is a reversible inhibitor of tyrosinase with an IC50 value of 15 mM .
    2-Ketoglutaric acid potassium
  • HY-W013636
    2-Ketoglutaric acid
    4 Publications Verification

    Alpha-Ketoglutaric acid; 2-Oxoglutaric acid

    Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid
  • HY-W013636B
    Calcium 2-oxoglutarate
    4 Publications Verification

    Tyrosinase Endogenous Metabolite Metabolic Disease
    Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    Calcium 2-oxoglutarate
  • HY-W013636A
    2-Ketoglutaric acid Sodium
    4 Publications Verification

    Alpha-Ketoglutaric acid Sodium

    Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid Sodium
  • HY-156964

    Bacterial Endogenous Metabolite Cancer
    Benzmalecene is a Krebs cycle inhibitor, and inhibits the active absorption of taurocholate by the small intestine in vivo and in vitro .
    Benzmalecene
  • HY-44134R

    Endogenous Metabolite Others
    Felypressin (Standard) is the analytical standard of Felypressin. This product is intended for research and analytical applications. Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures .
    Dimethyl 2-oxoglutarate (Standard)
  • HY-163771

    Pyruvate Carboxylase (PC) Metabolic Disease
    Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose .
    Pyruvate Carboxylase-IN-5
  • HY-W013636AR

    Alpha-Ketoglutaric acid Sodium (Standard)

    Reference Standards Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid Sodium (Standard)
  • HY-W250310

    L-Arginine alpha-ketoglutarate

    Biochemical Assay Reagents Others
    L-Arginine α-ketoglutarate, often abbreviated as AAKG, is a dietary supplement that combines arginine L-Arginine and α-ketoglutarate, a key intermediate in the Krebs cycle. L-arginine is a precursor of nitric oxide, which regulates blood flow and promotes vasodilation, while α-ketoglutarate is involved in energy production and protein synthesis. Together, these compounds are thought to support improved muscle recovery, increased endurance, and enhanced athletic performance.
    L-Arginine α-ketoglutarate
  • HY-W013636S1

    Alpha-Ketoglutaric acid-d4

    Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid-d4 (Alpha-Ketoglutaric acid-d4) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid-d4
  • HY-W013636S2

    Alpha-Ketoglutaric acid-d6

    Tyrosinase Endogenous Metabolite Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    2-Ketoglutaric acid-d6 (Alpha-Ketoglutaric acid-d6) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid-d6
  • HY-W013636S

    Alpha-Ketoglutaric acid-13C5

    Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid- 13C5 (Alpha-Ketoglutaric acid- 13C5) is a 13C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid-13C5
  • HY-W013636S3

    Alpha-Ketoglutaric acid-13C

    Isotope-Labeled Compounds Endogenous Metabolite Tyrosinase Neurological Disease Metabolic Disease
    2-Ketoglutaric acid- 13C (Alpha-Ketoglutaric acid- 13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid-13C
  • HY-W013636AG

    Alpha-Ketoglutaric acid Sodium

    Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid Sodium
  • HY-W013636S4

    Alpha-Ketoglutaric acid-13C2

    Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid- 13C2 (Alpha-Ketoglutaric acid- 13C2) is a 13C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid-13C2
  • HY-W013636R
    2-Ketoglutaric acid (Standard)
    4 Publications Verification

    Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)

    Reference Standards Tyrosinase Endogenous Metabolite Neurological Disease Metabolic Disease
    2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
    2-Ketoglutaric acid (Standard)

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