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Results for "

KPT 330

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17536
    Selinexor
    5 Publications Verification

    KPT-330

    		 CRM1 Cancer
    Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor .
    Selinexor
  • HY-17536R
    Selinexor (Standard)

    KPT-330 (Standard)

    		 Reference Standards CRM1 Cancer
    Selinexor (Standard) is the analytical standard of Selinexor. This product is intended for research and analytical applications. Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor .
    Selinexor (Standard)
  • HY-17536S
    Selinexor-d5

    KPT-330-d5

    		 Isotope-Labeled Compounds CRM1 Cancer
    Selinexor-d5 (KPT-330-d5) isthe deuterium labeled Selinexor (HY-17536). Selinexor (KPT-330), an analog of KPT-185, is an orally active and selective CRM1 inhibitor .
    Selinexor-d5
  • HY-17536A
    (E)-Selinexor

    (E)-KPT-330

    		 CRM1 Cancer
    (E)-Selinexor ((E)-KPT-330) is the E-isomer of Selinexor (HY-17536). Selinexor is the selective, orally active CRM1 inhibitor .
    (E)-Selinexor
  • HY-W338346
    Salicylate choline

    		Drug Derivative Interleukin Related TNF Receptor Polo-like Kinase (PLK) Inflammation/Immunology Cancer
    Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer .
    Salicylate choline

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