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KC-289

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175416

    KC289

    Piezo Channel NO Synthase Metabolic Disease
    Yoda2 (KC289) is the potassium salt of Yoda1 (HY-18723). Yoda2 is an agonist of PIEZO1 with an EC50 of 150 nM. Yoda2 evokes Ca 2+ elevation in HeLa cells. Yoda2 can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50 = 1.2 μM). Yoda2 can stimulate NOS3 and NO production .
    Yoda2

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