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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

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Integrin b2/ITGB2/CD18 Antibody

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3962

Inhibitors & Agonists

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205

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212

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161

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2318

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Natural
Products

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4931

Antibodies

266

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139

Oligonucleotides

Targets Recommended: Integrin ADC Antibody Antibody-Drug Conjugates (ADCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990288

Anti-Mouse CD18 Antibody (M18/2)	Integrin	Others
Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD18.

HY-N0796R

Procyanidin B2 (Standard) 10+ Cited Publications Proanthocyanidin b2 (Standard)	Reactive Oxygen Species	Cancer
Procyanidin B2 (Standard) is the analytical standard of Procyanidin B2. This product is intended for research and analytical applications. Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-113331

Thromboxane B2	Prostaglandin Receptor	Inflammation/Immunology
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.

HY-113042

Prostaglandin B2	Endogenous Metabolite	Cardiovascular Disease Endocrinology
Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw ^[2].

HY-N0796

Procyanidin B2 10+ Cited Publications Proanthocyanidin b2	Reactive Oxygen Species	Cancer
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-RS16847

Itgb2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Itgb2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Itgb2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Itgb2 Mouse Pre-designed siRNA Set A Itgb2 Mouse Pre-designed siRNA Set A

HY-RS23288

Itgb2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Itgb2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Itgb2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Itgb2 Rat Pre-designed siRNA Set A Itgb2 Rat Pre-designed siRNA Set A

HY-RS06965

ITGB2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ITGB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ITGB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ITGB2 Human Pre-designed siRNA Set A ITGB2 Human Pre-designed siRNA Set A

HY-N14277

Miyakamide B2	Antibiotic Bacterial	Infection Cancer
Miyakamide B2 is an antibiotic with insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina. Miyakamide B2 has a weak antixanthomonas activity. Miyakamide B2 inhibits P388 cells with an IC₅₀ of 7.6 μg/mL .

HY-N14420

Parvodicin B2	Antibiotic Bacterial	Infection
Parvodicin B2 is a glycopeptide antibiotic. Parvodicin B2 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis. Parvodicin B2 acts by inhibiting the synthesis of bacterial cell wall .

HY-N14468

Pneumocandin B2	Antibiotic Bacterial	Infection
Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14804

Napyradiomycin B2	Antibiotic Bacterial	Infection
Napyradiomycin B2 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B2 almost none to Gram-negative bacteria and fungi .

HY-N13981

Arylomycin B2	Antibiotic Bacterial	Infection
Arylomycin B2, an antibiotic, is a potent signal peptidase I (SPase I) inhibitor. Arylomycin B2 has anti-Gram-positive bacteria activities .

HY-N14564

Cycloviracin B2	Antibiotic HSV	Infection
Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .

HY-A0248B

Polymyxin B2	Antibiotic Bacterial	Infection
Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .

HY-N0248R

Saikosaponin B2 (Standard)	HCV	Infection Cancer
Saikosaponin B2 (Standard) is the analytical standard of Saikosaponin B2. This product is intended for research and analytical applications. Saikosaponin B2 is an active component from Bupleurum chinensis root, acts as an entry inhibitor against HCV infection . Anti-cancer activity ^[2].

HY-N14282

Ezomycin B2	Antibiotic Fungal	Infection
Ezomycin B2 is an antibiotic with antifungal activity .

HY-N14297

Fluvirucin B2	Antibiotic Influenza Virus	Infection
Fluvirucin B2 is an antibiotic against influenza A virus .

HY-N6731

Hydrolyzed Fumonisin B2	Others	Infection
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

HY-113420

11-Dehydro-thromboxane B2	Endogenous Metabolite	Metabolic Disease
11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis ^[2].

HY-N6256

Ilexsaponin B2	Phosphodiesterase (PDE)	Cardiovascular Disease
Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC₅₀ values of 48.8 μM and 477.5 μM, respectively .

HY-N8200

Cassiaside B2	Phosphatase Monoamine Oxidase 5-HT Receptor	Inflammation/Immunology
Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a *5-HT2C* receptor agonist ^[2]. ..

HY-A0248C

Polymyxin B2 Sulfate	Antibiotic Bacterial	Infection
Polymyxin B2 Sulfate is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 Sulfate kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 Sulfate can be used in antibiotic development and treatment of drug-resistant strains .

HY-N14042

Arizonin B2	Bacterial	Infection
Arizonin B2 is a microbial metabolite with anti-Gram-positive bacterial activities .

HY-N14839

Neoenactin B2	Fungal	Infection
Neoenactin B2 has strong anti-yeastlike and filamentous fungal effects .

HY-W749297

Bleomycin B2 Phleomycin D2	DNA Stain	Cancer
Bleomycin B2 (Phleomycin D2) is an anti-cancer agent that targets DNA. Bleomycin B2 causes DNA strand breaks, thereby inhibiting the growth and proliferation of cancer cells. Bleomycin B2 is promising for research of cancers .

HY-N12221

Cinnamtannin B2	Others	Others
Cinnamtannin B2 (compound 12) is a cinnamon tannin isolated from Vaccinium vitis-idaea L .

HY-N12390

Alternaphenol B2	Isocitrate Dehydrogenase (IDH)	Cancer
Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC₅₀ values of 41.9 μM .

HY-N14744

Lanopylin B2	Others	Infection
Lanopylin B2 can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with an IC₅₀ of 41 μM .

HY-127014

Julimycin B2	Bacterial	Infection Cancer
Julimycin B2 has anti-Gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice .

HY-N0248

Saikosaponin B2	HCV	Infection Cancer
Saikosaponin B2 is an active component from Bupleurum chinensis root, acts as an entry inhibitor against HCV infection . Anti-cancer activity ^[2].

HY-N12590

6′′-O-Acetylsaikosaponin b2	Others	Others
6′′-O-Acetylsaikosaponin b2 (compound 11) is a natural saikosaponin found in Bupleurum chinense .

HY-N6723

Fumonisin B2	Acyltransferase	Infection
Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis ^[2].

HY-P2783

Destruxin B2	HBV	Infection
Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC₅₀ 1.30 μM .

HY-N9790

Procyanidin B2 3,3'-di-O-gallate	Notch	Others
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .

HY-105350

Pristinamycin IB Ostreogrycin b2 ; Vernamycin Bβ	Antibiotic Bacterial	Infection
Pristinamycin IB (Ostreogrycin B2) is an ester peptide antibiotic with anti-Gram-positive bacteria effects .

HY-P5708

Adenoregulin Dermaseptin b2	Antibiotic Fungal Bacterial	Infection
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-N0044

Ginsenoside Re 2 Publications Verification Ginsenoside b2; Panaxoside Re; Sanchinoside Re	Amyloid-β NF-κB JNK Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.

HY-P99891

Rovelizumab 1 Publications Verification	Integrin	Cardiovascular Disease
Rovelizumab is a humanized monoclonal leukointegrin antibody. Rovelizumab is a monoclonal antibody directed against the *CD11/CD18* cell adhesion proteins. Rovelizumab can be used for research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI) and stroke .

HY-126923

2,3-Dinor thromboxane B2 2,3-Dinor-TXb2	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
2,3-Dinor thromboxane B2 (2,3-Dinor-TXB2), a metabolite of urine, serves as an indicator of the production of thromboxane A2 (TxA2) in the body, and can be used as a tool to study the role of thromboxane in various pathophysiological processes in the human body .

HY-14648A

Dexamethasone acetate 5 Publications Verification Dexamethasone 21-acetate; Hexadecadrol acetate	Glucocorticoid Receptor Autophagy Mitophagy Bacterial SARS-CoV Antibiotic Complement System ADC Cytotoxin	Inflammation/Immunology Endocrinology Cancer
Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-14648S5

Dexamethasone-d3-1 Hexadecadrol-d₃-1; Prednisolone F-d₃-1	Isotope-Labeled Compounds Antibiotic Autophagy Glucocorticoid Receptor SARS-CoV ADC Cytotoxin Mitophagy Complement System Bacterial	Cancer
Dexamethasone-d₃-1 (Hexadecadrol-d₃-1; Prednisolone F-d₃-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-137555

11-dehydro-2,3-dinor Thromboxane B2 11-dehydro-2,3-dinor TXb2	Endogenous Metabolite	Metabolic Disease
11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.

HY-15701

Leukadherin-1 3 Publications Verification	Integrin Complement System	Inflammation/Immunology
Leukadherin-1, a specific agonist of the leukocyte surface integrin *CD11b/CD18, increases CD11b/CD18*-dependent cell adhesion to fibrinogen with an EC₅₀ of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling ^[2] .

HY-113331S1

Thromboxane B2-d9	Isotope-Labeled Compounds Prostaglandin Receptor	Inflammation/Immunology
Thromboxane B2-d₉ is deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation .

HY-113331S

Thromboxane B2-d4	Isotope-Labeled Compounds	Inflammation/Immunology
Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation ^[2].

HY-113042S

Prostaglandin B2-d4	Isotope-Labeled Compounds	Others
Prostaglandin B2-d₄ is the deuterium labeled Prostaglandin B2 .

HY-14648S2

Dexamethasone-d4 Hexadecadrol-d₄; Prednisolone F-d₄	Isotope-Labeled Compounds Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic	Infection Inflammation/Immunology Endocrinology Cancer
Dexamethasone-d₄ is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-14648S1

Dexamethasone-d5-1 Hexadecadrol-d₅-1; Prednisolone F-d₅-1	Isotope-Labeled Compounds Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic	Infection Inflammation/Immunology Endocrinology Cancer
Dexamethasone-d₅-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-113420S2

11-Dehydro-thromboxane B2-13C5	Endogenous Metabolite Isotope-Labeled Compounds	Metabolic Disease
11-Dehydro-thromboxane B2- ¹³C₅ is ¹³C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis ^[2].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0796R

Procyanidin B2 (Standard) 10+ Cited Publications Proanthocyanidin b2 (Standard)	Structural Classification Flavonoids other families Functional Molecules Classification of Application Fields Source classification Research of Health Products Phenols Plants Disease Research Fields Cancer	Reactive Oxygen Species
Procyanidin B2 (Standard) is the analytical standard of Procyanidin B2. This product is intended for research and analytical applications. Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-113042

Prostaglandin B2	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw ^[2].

HY-N0796

Procyanidin B2 10+ Cited Publications Proanthocyanidin b2	Structural Classification Classification of Application Fields Source classification Plants Flavonoids other families Functional Molecules Research of Health Products Phenols Polyphenols Biflavones Disease Research Fields Cancer	Reactive Oxygen Species
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-N14277

Miyakamide B2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Miyakamide B2 is an antibiotic with insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina. Miyakamide B2 has a weak antixanthomonas activity. Miyakamide B2 inhibits P388 cells with an IC₅₀ of 7.6 μg/mL .

HY-N14420

Parvodicin B2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Parvodicin B2 is a glycopeptide antibiotic. Parvodicin B2 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis. Parvodicin B2 acts by inhibiting the synthesis of bacterial cell wall .

HY-N14468

Pneumocandin B2	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial
Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14804

Napyradiomycin B2	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial
Napyradiomycin B2 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B2 almost none to Gram-negative bacteria and fungi .

HY-N13981

Arylomycin B2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Arylomycin B2, an antibiotic, is a potent signal peptidase I (SPase I) inhibitor. Arylomycin B2 has anti-Gram-positive bacteria activities .

HY-N14564

Cycloviracin B2	Structural Classification Natural Products Microorganisms Source classification	Antibiotic HSV
Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .

HY-N0248R

Saikosaponin B2 (Standard)	Triterpenes Structural Classification Terpenoids Source classification Umbelliferae Plants Carphephorus corymbosus (Nutt.) Torr. & A.Gray	HCV
Saikosaponin B2 (Standard) is the analytical standard of Saikosaponin B2. This product is intended for research and analytical applications. Saikosaponin B2 is an active component from Bupleurum chinensis root, acts as an entry inhibitor against HCV infection . Anti-cancer activity ^[2].

HY-N14282

Ezomycin B2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Ezomycin B2 is an antibiotic with antifungal activity .

HY-N14297

Fluvirucin B2	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Influenza Virus
Fluvirucin B2 is an antibiotic against influenza A virus .

HY-N6731

Hydrolyzed Fumonisin B2	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Others
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

HY-113420

11-Dehydro-thromboxane B2	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis ^[2].

HY-N6256

Ilexsaponin B2	Cardiovascular Disease Aquifoliaceae Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Ilex pubescens Hook. et Arn. Plants Disease Research Fields	Phosphodiesterase (PDE)
Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC₅₀ values of 48.8 μM and 477.5 μM, respectively .

HY-N8200

Cassiaside B2	Structural Classification Monophenols Classification of Application Fields Cassia obtusifolia L. Source classification Phenols Caesalpiniaceae Plants Inflammation/Immunology Disease Research Fields	Phosphatase Monoamine Oxidase 5-HT Receptor
Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a *5-HT2C* receptor agonist ^[2]. ..

HY-N14042

Arizonin B2	Quinones Structural Classification Microorganisms Source classification Naphthalene Quinones	Bacterial
Arizonin B2 is a microbial metabolite with anti-Gram-positive bacterial activities .

HY-N14839

Neoenactin B2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Neoenactin B2 has strong anti-yeastlike and filamentous fungal effects .

HY-W749297

Bleomycin B2 Phleomycin D2	Structural Classification Natural Products Microorganisms Source classification	DNA Stain
Bleomycin B2 (Phleomycin D2) is an anti-cancer agent that targets DNA. Bleomycin B2 causes DNA strand breaks, thereby inhibiting the growth and proliferation of cancer cells. Bleomycin B2 is promising for research of cancers .

HY-N12221

Cinnamtannin B2	Structural Classification Vaccinium vitis-idaea L. Source classification Phenols Polyphenols Plants Ericaceae	Others
Cinnamtannin B2 (compound 12) is a cinnamon tannin isolated from Vaccinium vitis-idaea L .

HY-N12390

Alternaphenol B2	Structural Classification Microorganisms Source classification Phenols Polyphenols	Isocitrate Dehydrogenase (IDH)
Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC₅₀ values of 41.9 μM .

HY-N14744

Lanopylin B2	Structural Classification Natural Products Microorganisms Source classification	Others
Lanopylin B2 can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with an IC₅₀ of 41 μM .

HY-127014

Julimycin B2	Structural Classification Monophenols Microorganisms Source classification Phenols	Bacterial
Julimycin B2 has anti-Gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice .

HY-N0248

Saikosaponin B2	Infection Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Umbelliferae Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	HCV
Saikosaponin B2 is an active component from Bupleurum chinensis root, acts as an entry inhibitor against HCV infection . Anti-cancer activity ^[2].

HY-N12590

6′′-O-Acetylsaikosaponin b2	Triterpenes Structural Classification Sonchus asper (L.) Hill Terpenoids Source classification Umbelliferae Plants	Others
6′′-O-Acetylsaikosaponin b2 (compound 11) is a natural saikosaponin found in Bupleurum chinense .

HY-N6723

Fumonisin B2	Infection Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Disease Research Fields Other Antibiotics	Acyltransferase
Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis ^[2].

HY-P2783

Destruxin B2	Structural Classification Microorganisms Cyclopeptides Source classification	HBV
Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC₅₀ 1.30 μM .

HY-N9790

Procyanidin B2 3,3'-di-O-gallate	Structural Classification Source classification Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae	Notch
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .

HY-105350

Pristinamycin IB Ostreogrycin b2 ; Vernamycin Bβ	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Pristinamycin IB (Ostreogrycin B2) is an ester peptide antibiotic with anti-Gram-positive bacteria effects .

HY-P5708

Adenoregulin Dermaseptin b2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-N0044

Ginsenoside Re 2 Publications Verification Ginsenoside b2; Panaxoside Re; Sanchinoside Re	Panax ginseng C. A. Meyer Triterpenes Structural Classification Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer	Amyloid-β NF-κB JNK Endogenous Metabolite
Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.

HY-B0456

Riboflavin 3 Publications Verification Vitamin b2; E101	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .

HY-B0579

Cyclosporin A Maximum Cited Publications 128 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Structural Classification Natural Products Microorganisms Classification of Application Fields Anti-aging Source classification Inflammation/Immunology Disease Research Fields Cancer	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-B0579R

Cyclosporin A (Standard)	Structural Classification Natural Products Microorganisms Source classification	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N13984

Arylomycin B5	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Arylomycin B5, a microbial metabolite, is a structural analog of Arylomycin B2 (HY-N13981) .

HY-N13982

Arylomycin B3	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Arylomycin B3, a microbial metabolite, is a structural analog of Arylomycin B2 (HY-N13981) .

HY-N0652

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside 1 Publications Verification 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside	Structural Classification Stilbenes Classification of Application Fields Polygonaceae Source classification Other Diseases Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants Disease Research Fields	ERK NF-κB
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions ^[2].

HY-N0044R

Ginsenoside Re (Standard) Ginsenoside b2(Standard); Panaxoside Re(Standard); Sanchinoside Re (Standard)	Panax ginseng C. A. Meyer Structural Classification Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer	Amyloid-β NF-κB JNK Endogenous Metabolite
Ginsenoside Re (Standard) is the analytical standard of Ginsenoside Re. This product is intended for research and analytical applications. Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.

HY-N5031

Mulberrofuran Q	other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Mulberrofuran Q inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products) .

HY-N3617

Coniferin 1 Publications Verification Laricin	Infection Structural Classification Microorganisms other families Classification of Application Fields Simple Phenylpropanols Source classification Phenylpropanoids Plants Disease Research Fields	Fungal Prostaglandin Receptor
Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal melanization. Coniferin inhibits the release of certain hormones from cells, including Prostaglandin E2 and Thromboxane B2 ^[2] .

HY-N2391

p-Hydroxycinnamic acid	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite Prostaglandin Receptor
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC₅₀s of 371 μM, 126 μM for thromboxane B₂ production and lipopolysaccharide-induced prostaglandin E₂ generation, respectively.

HY-N0604

Ginsenoside Rh1 4 Publications Verification Prosapogenin A2; Sanchinoside b2; Sanchinoside Rh1	Panax ginseng C. A. Meyer Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Araliaceae	Interleukin Related PPAR TNF Receptor Endogenous Metabolite
Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.

HY-B0964A

Riboflavin phosphate Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism ^[2]. Riboflavine phosphate is a very effective NAD ⁺-recycling agent .

HY-B0964

Riboflavin phosphate sodium Riboflavine phosphate sodium; Riboflavin 5'-phosphate sodium; Riboflavine 5'-phosphate sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism ^[2]. Riboflavine phosphate sodium is a very effective NAD ⁺-recycling agent .

HY-W013713

Riboflavin phosphate sodium hydrate Riboflavine phosphate sodium hydrate; Riboflavin 5'-phosphate sodium hydrate; Riboflavine 5'-phosphate sodium hydrate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavine phosphate sodium hydrate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism ^[2]. Riboflavine phosphate sodium hydrate is a very effective NAD ⁺-recycling agent .

HY-N0652R

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Standard)	Structural Classification Stilbenes Polygonaceae Source classification Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants	ERK NF-κB
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Standard) is the analytical standard of 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside. This product is intended for research and analytical applications. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions ^[2].

HY-N3617R

Coniferin (Standard) Laricin (Standard)	Structural Classification Microorganisms other families Simple Phenylpropanols Source classification Phenylpropanoids Plants	Fungal
Coniferin (Standard) is an analytical standard for Coniferin. This product is intended for research and analytical applications. Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal melanization. Coniferin inhibits the release of certain hormones from cells, including Prostaglandin E2 and Thromboxane B2 ^[2] .

HY-B0964R

Riboflavin phosphate (sodium) (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Riboflavin phosphate (sodium) (Standard) is the analytical standard of Riboflavin phosphate (sodium). This product is intended for research and analytical applications. Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism ^[2]. Riboflavine phosphate sodium is a very effective NAD+-recycling agent .

HY-N0604R

Ginsenoside Rh1 (Standard) Prosapogenin A2 (Standard); Sanchinoside b2 (Standard); Sanchinoside Rh1 (Standard)	Panax ginseng C. A. Meyer Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Araliaceae	Interleukin Related PPAR TNF Receptor Endogenous Metabolite
Ginsenoside Rh1 (Standard) is the analytical standard of Ginsenoside Rh1. This product is intended for research and analytical applications. Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.

HY-125122

Mulberrofuran A	Structural Classification Monophenols Source classification Phenols Morus alba L. Plants Moraceae	Others
Mulberrofuran A is a natural product, that can be isolated from the root bark of mulberry tree. Mulberrofuran A inhibits the formations of 12-hydroxy-,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products), but it increases the formation of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product) .

Cat. No.	Product Name	Chemical Structure

HY-14648S5

Dexamethasone-d3-1

Dexamethasone-d₃-1 (Hexadecadrol-d₃-1; Prednisolone F-d₃-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-14648S

Dexamethasone-d5

Dexamethasone-d₅ is the deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses ^[2].

HY-113331S1

Thromboxane B2-d9
Thromboxane B2-d₉ is deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation .

HY-113331S

Thromboxane B2-d4
Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation ^[2].

HY-113042S

Prostaglandin B2-d4
Prostaglandin B2-d₄ is the deuterium labeled Prostaglandin B2 .

HY-14648S2

Dexamethasone-d4

Dexamethasone-d₄ is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-14648S1

Dexamethasone-d5-1

Dexamethasone-d₅-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-113420S2

11-Dehydro-thromboxane B2-13C5
11-Dehydro-thromboxane B2- ¹³C₅ is ¹³C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis ^[2].

HY-113420S

11-Dehydro-thromboxane B2-d4
11-Dehydro-thromboxane B2-d₄ is the deuterium labeled 11-Dehydro-thromboxane B2 .

HY-N6723S

Fumonisin B2-13C34
Fumonisin B2- ¹³C₃₄ is the ¹³C labeled Fumonisin B2 (HY-N6723) . Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis ^[2] .

HY-14648S3

Dexamethasone-4,6α,21,21-d4

Dexamethasone-4,6α,21,21-d₄ is the deuterium labeled Dexamethasone-4,6α,21,21. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-165674S

11-dehydro-2,3-dinor Thromboxane B2-d9
11-dehydro-2,3-dinor Thromboxane B2-d₉ (11-dehydo-2,3-dio TXB2-d₉) is deuterium labeled 11-dehydro-2,3-dinor Thromboxane B2 .

HY-B0579S5

Cyclosporin A-d12
Cyclosporin A-d₁₂ (Cyclosporine A-d₁₂) is deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-B0579S2

Cyclosporin A acetate-d4
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM ^[2]. Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-B0456S5

Riboflavin-d8
Riboflavin-d₈ (Vitamin B2-d₈ ) is deuterium labeled Riboflavin. Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .

HY-B0579S3

Cyclosporin A-13C2,d4

Cyclosporin A- ¹³C₂,d₄ (Cyclosporine A- ¹³C₂,d₄; Ciclosporin A- ¹³C₂,d₄) is a ¹³C labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM ^[2]. Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-173107S

Haemoglobin HbA0 (a2b2), U-15N
Haemoglobin HbA0 (a2b2), U- ¹⁵N is the ¹⁵N-labeled Haemoglobin Haemoglobin HbA0 (a2b2), U.

HY-19344S2

Lifitegrast-d4-1

Lifitegrast-d₄-1 is deuterium labeled Lifitegrast. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC₅₀ of 2.98 nM. Lifitegrast can be used for researching dry eye disease ^[2].

HY-113439S

12-HETE-d8
12-HETE-d₈ is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway .12-HETE has both anti-thrombotic and pro-thrombotic effects ^[2]. 12-HETE is a neuromodulator .

HY-19344S1

Lifitegrast-d6

Lifitegrast-d₆ (SAR 1118-d₆) is deuterium labeled Lifitegrast. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC₅₀ of 2.98 nM. Lifitegrast can be used for researching dry eye disease ^[2].

HY-19344S

Lifitegrast-d4

Lifitegrast-d₄ (SAR 1118-d₄) is deuterium labeled Lifitegrast. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC₅₀ of 2.98 nM. Lifitegrast can be used for researching dry eye disease ^[2].

HY-P5168S

GPSVFPLAPSSK-13C6,15N2
GPSVFPLAPSSK- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies ^[2].

HY-P5168AS

GPSVFPLAPSSK-13C6,15N2 TFA
GPSVFPLAPSSK- ¹³C₆, ¹⁵N₂ TFA is the ¹³C- and ¹⁵N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies ^[2].

HY-152003S

Ganglioside GM2-d3 ammonium

Ganglioside GM2-d₃ (ammonium) is the deuterium labeled Ganglioside GM2 (HY-148385). Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling ^[2] .

HY-W142395S

6-TAMRA-d12 free acid
6-TAMRA-d₁₂ free acid is a deuterated-labeled 6-TAMRA, which is widely used in the preparation of fluorescent antibodies and as a fluorescent group for immunohistochemical avidin derivatives.

HY-16567S

Asenapine-13C,d3 hydrochloride
Asenapine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Asenapine (hydrochloride). Asenapine hydrochloride, an antipsychotic, is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D2, D3, D4) receptor antagonist with Ki values of 0.03-4.0 nM for 5-HT and 1.3, 0.42, 1.1 nM for Dopamine receptor, respectively.

HY-B0456S3

Riboflavin-d3
Riboflavin-d₃ is the deuterium labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-12454S

DM4-d6
DM4-d₆ is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

HY-W001909S

Myosmine-d4
Myosmine-d₄ is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a K_i of 3300 nM ^[2].

HY-I1129

Fmoc-3VVD-OH-d8
Fmoc-3VVD-OH-d₈ is a deuterium labeled Fmoc-3VVD-OH (HY-78921). Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P5201S1

VTSEGAGLQLQK-13C6,15N2 TFA
VTSEGAGLQLQK- ¹³C₆, ¹⁵N₂ (TFA) is the ¹³C- and ¹⁵N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect ^[2].

HY-P5201S

VTSEGAGLQLQK-13C6,15N2
VTSEGAGLQLQK- ¹³C₆, ¹⁵N₂ is the ¹³C and ¹⁵N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect ^[2].

HY-B0199S

Mycophenolate Mofetil-d4

Mycophenolate Mofetil-d₄ is the deuterium labeled Mycophenolate Mofetil. Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation .

HY-B0456S2

Riboflavin-13C5
Riboflavin- ¹³C₅ is the ¹³C-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-145397S

(4-NH2)-Exatecan-d5
(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan . (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) ^[2].

HY-114816S

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d₅ is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa ^[2] .

HY-161022S1

FL118-C3-O-C-amide-C-NH2-d5 formate
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-B0456S

Riboflavin-13C4,15N2
Riboflavin- ¹³C₄, ¹⁵N₂is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-B0456S1

Riboflavin-5-Phosphate-13C4,15N2-1
Riboflavin-5-Phosphate- ¹³C₄, ¹⁵N₂-1 is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

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