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Indole (standard)

" in MedChemExpress (MCE) Product Catalog:

34

Inhibitors & Agonists

2

Biochemical Assay Reagents

28

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W001132R
    Indole (standard)
    1 Publications Verification

    Reference Standards Endogenous Metabolite Infection
    Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
    Indole (standard)
  • HY-I0096R

    Endogenous Metabolite iGluR Reference Standards Neurological Disease
    Indole-2-carboxylic acid (Standard) is the analytical standard of Indole-2-carboxylic acid. This product is intended for research and analytical applications. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current .
    Indole-2-carboxylic acid (Standard)
  • HY-40161R

    Reference Standards Endogenous Metabolite Metabolic Disease
    Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .
    Indole-3-carboxylic acid (Standard)
  • HY-N0186R

    Indolebutyric acid (standard)

    Reference Standards Endogenous Metabolite Others
    Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
    Indole-3-butyric acid (Standard)
  • HY-113099R

    Indole-3-lactic acid (standard)

    Reference Standards Endogenous Metabolite Inflammation/Immunology
    Indolelactic acid (Standard) is the analytical standard of Indolelactic acid. This product is intended for research and analytical applications. Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity[1][3][4].
    Indolelactic acid (Standard)
  • HY-33893R

    Endogenous Metabolite Metabolic Disease
    Indole-3-methanamine (Standard) is the analytical standard of Indole-3-methanamine. This product is intended for research and analytical applications. Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product .
    Indole-3-methanamine (Standard)
  • HY-W016784R

    Reference Standards Endogenous Metabolite Others
    Indole-3-acetamide (Standard) is the analytical standard of Indole-3-acetamide. This product is intended for research and analytical applications. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[1].
    Indole-3-acetamide (Standard)
  • HY-W028393R

    Reference Standards Endogenous Metabolite Aryl Hydrocarbon Receptor Neurological Disease Inflammation/Immunology
    Indole-3-pyruvic acid (Standard) is the analytical standard of Indole-3-pyruvic acid. This product is intended for research and analytical applications. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety[1][2][3].
    Indole-3-pyruvic acid (Standard)
  • HY-N0170R

    NF-κB Aryl Hydrocarbon Receptor E1/E2/E3 Enzyme Endogenous Metabolite Cancer
    Indole-3-carbinol (Standard) is the analytical standard of Indole-3-carbinol. This product is intended for research and analytical applications. Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
    Indole-3-carbinol (Standard)
  • HY-W007376R

    3-FormylIndole (standard)

    Reference Standards Endogenous Metabolite Others
    Indole-3-carboxaldehyde (Standard) is the analytical standard of Indole-3-carboxaldehyde. This product is intended for research and analytical applications. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract[1][2].
    Indole-3-carboxaldehyde (Standard)
  • HY-W010155R

    Indole-3-ethanol (standard)

    Reference Standards Endogenous Metabolite Apoptosis Caspase Bacterial Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
    Tryptophol (Standard) (Indole-3-ethanol (Standard)) is an analytical standard of Tryptophol (HY-W010155). This product is intended for use in research and analytical applications.Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces Apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy.
    Tryptophol (Standard)
  • HY-N2021AR

    Reference Standards MMP Angiotensin-converting Enzyme (ACE) Neprilysin Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
    Phosphoramidon Disodium (Standard)
  • HY-79635R

    Reference Standards Bacterial Infection
    Tiagabine (hydrochloride) (Standard) is the analytical standard of Tiagabine (hydrochloride). This product is intended for research and analytical applications. Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .
    Methyl indole-3-carboxylate (Standard)
  • HY-147063R

    Reference Standards Endogenous Metabolite Others
    Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
    N-Acetyl-α-D-glucosamine 1-phosphate disodium (Standard)
  • HY-18569AR

    Indole-3-acetic acid sodium (standard); 3-IAA sodium (standard)

    Reference Standards Endogenous Metabolite Metabolic Disease
    Ginsenoside F1 (Standard) is the analytical standard of Ginsenoside F1. This product is intended for research and analytical applications. Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.
    3-Indoleacetic acid sodium (Standard)
  • HY-18569R
    3-Indoleacetic acid (standard)
    Maximum Cited Publications
    13 Publications Verification

    Indole-3-acetic acid (standard); 3-IAA (standard)

    Molecular Glues Reference Standards Endogenous Metabolite Others
    3-Indoleacetic acid (Standard) is the analytical standard of 3-Indoleacetic acid. This product is intended for research and analytical applications. 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
    3-Indoleacetic acid (standard)
  • HY-W015229R

    Indole-3-propionic acid (standard); 3-IPA (standard)

    Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Neurological Disease Metabolic Disease
    3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .
    3-Indolepropionic acid (Standard)
  • HY-W007355R

    3-MethylIndole (standard); 3-Methyl-1H-Indole (standard)

    Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis Others
    Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .
    Skatole (Standard)
  • HY-B2132R
    Tryptamine (Standard)
    1 Publications Verification

    3-(2-Aminoethyl)Indole~2-(3-Indolyl)ethylamine (standard)

    Endogenous Metabolite Others
    Tryptamine (Standard) is the analytical standard of Tryptamine. This product is intended for research and analytical applications. Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
    Tryptamine (Standard)
  • HY-12392R

    5-HT Receptor Neurological Disease Metabolic Disease
    Iprindole (Standard) is the analytical standard of Iprindole. This product is intended for research and analytical applications. Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT .
    Iprindole (Standard)
  • HY-113440R

    Endogenous Metabolite Neurological Disease
    5-Methoxytryptophol (Standard) is the analytical standard of 5-Methoxytryptophol. This product is intended for research and analytical applications. 5-Methoxytryptophol is a natural indole present in the pineal gland.
    5-Methoxytryptophol (Standard)
  • HY-N0117R

    Couroupitine B (standard); Indigo red (standard); Indigopurpurin (standard)

    Reference Standards Apoptosis Cancer
    Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    Indirubin (Standard)
  • HY-N0275R

    Topoisomerase Cancer
    (±)-10-Hydroxycamptothecin (Standard) is the analytical standard of (±)-10-Hydroxycamptothecin. This product is intended for research and analytical applications. (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.
    (±)-10-Hydroxycamptothecin (Standard)
  • HY-116425R

    Alanap 1 (standard)

    Herbicide Reference Standards Others
    N-1-Naphthylphthalamic acid (Standard) is the analytical standard of N-1-Naphthylphthalamic acid. This product is intended for research and analytical applications. N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation .
    N-1-Naphthylphthalamic acid (Standard)
  • HY-N4173R

    Reference Standards Drug Metabolite Metabolic Disease
    p-Dimethylaminobenzaldehyde (Standard) is the analytical standard of p-Dimethylaminobenzaldehyde. This product is intended for research and analytical applications. p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles .
    8-Oxoepiberberine (Standard)
  • HY-W420344R

    Potassium Channel Reference Standards Others
    Dehydroindapamide (Standard) is the analytical standard of Dehydroindapamide. This product is intended for research and analytical applications. Dehydroindapamide is the indole form of Indapamide (HY-B0259). Dehydroindapamide standard can be used to quantitatively measure the Indapamide turnover rate by CYP3A4, which was approximately 10-fold higher than that of Indoline (HY-Y0788), and slightly enhanced affinity for CYP3A4 .
    Dehydroindapamide (Standard)
  • HY-34596R

    Biochemical Assay Reagents Reference Standards Others
    4-Hydroxyindole (Standard) is the analytical standard of 4-Hydroxyindole. This product is intended for research and analytical applications. 4-Hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. 4-Hydroxyindole is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers .
    4-Hydroxyindole (Standard)
  • HY-107486R

    Multhiomycin (standard); RP 9671 (standard)

    Reference Standards Bacterial Antibiotic Infection
    Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .
    Nosiheptide (Standard)
  • HY-W420344

    Potassium Channel Others
    Dehydroindapamide is the indole form of Indapamide (HY-B0259). Dehydroindapamide standard can be used to quantitatively measure the Indapamide turnover rate by CYP3A4, which was approximately 10-fold higher than that of Indoline (HY-Y0788), and slightly enhanced affinity for CYP3A4 .
    Dehydroindapamide
  • HY-N6607R

    Reference Standards Leukotriene Receptor NO Synthase NF-κB COX TNF Receptor Interleukin Related Inflammation/Immunology Cancer
    Tryptanthrin (Standard) is the analytical standard of Tryptanthrin. This product is intended for research and analytical applications. Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α .
    Tryptanthrin (Standard)
  • HY-144470S

    Isotope-Labeled Compounds Potassium Channel Others
    Dehydroindapamide-d3 is the deuterium labeled Dehydroindapamide (HY-W420344). Dehydroindapamide is the indole form of Indapamide (HY-B0259). Dehydroindapamide standard can be used to quantitatively measure the Indapamide turnover rate by CYP3A4, which was approximately 10-fold higher than that of Indoline (HY-Y0788), and slightly enhanced affinity for CYP3A4 .
    Dehydroindapamide-d3
  • HY-B1021R

    Reference Standards Free Fatty Acid Receptor Cardiovascular Disease Metabolic Disease
    Vincamine (Standard) is the analytical standard of Vincamine. This product is intended for research and analytical applications. Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .
    Vincamine (Standard)
  • HY-W001160R

    Reference Standards Endogenous Metabolite nAChR Calcium Channel Neurological Disease Endocrinology Cancer
    5-Hydroxyindole (Standard) is the analytical standard of 5-Hydroxyindole (HY-W001160). This product is intended for research and analytical applications. 5-Hydroxyindole is an orally active hydroxylated indole and tryptophan metabolite. 5-Hydroxyindole activates α7 nicotinic acetylcholine receptors and acts on intestinal L-type calcium channels. 5-Hydroxyindole slows down the desensitization of 5-HT3 receptor-mediated ion currents in cells. 5-Hydroxyindole causes convulsions and loss of consciousness. 5-Hydroxyindole is used in the study of neuroblastoma, schizophrenia, and diseases related to intestinal motility disorders .
    5-Hydroxyindole (Standard)
  • HY-Y0136R

    Reference Standards Endogenous Metabolite Influenza Virus HSV VSV Metabolic Disease
    3-Indoleacetonitrile (Standard) is the analytical standard of 3-Indoleacetonitrile. This product is intended for research and analytical applications. 3-Indoleacetonitrile is an indole derivative with anti-influenza activity. 3-Indoleacetonitrile is a plant hormone produced by cruxiferous vegetables. 3-Indoleacetonitrile exerts profound antiviral activity against a broad spectrum of influenza A viruses, HSV-1 and VSV viruses in vitro. 3-Indoleacetonitrile diminishes lung virus titers and alleviates lung lesions in vivo. 3-Indoleacetonitrile induces an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile can be used in research for combating viral infections including COVID-19, HSV-1, and VSV .
    3-Indoleacetonitrile (Standard)

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