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Results for "

ITP

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Inhibitory Antibodies

1

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013706
    Inosine-5'-triphosphate trisodium salt

    ITP trisodium salt; Inosine triphosphate trisodium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt
  • HY-P99730
    Mezagitamab
    1 Publications Verification

    TAK-079

    		 CD38 Apoptosis Inflammation/Immunology Cancer
    Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) .
    Mezagitamab
  • HY-145598
    Sovleplenib

    HMPL-523

    		 Syk Cancer
    Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP) .
    Sovleplenib
  • HY-150172A
    Inosine 5'-triphosphate lithium salt

    ITP lithium salt; Inosine triphosphate lithium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
    Inosine 5'-triphosphate lithium salt
  • HY-RS20758
    Itpa Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Itpa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Itpa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Itpa Mouse Pre-designed siRNA Set A
    Itpa Mouse Pre-designed siRNA Set A
  • HY-115755
    Thio-ITP

    6-Thioinosine 5′-triphosphate; 6-Mercaptopurine-riboside-5'-triphosphate; 6-Thio-ITP

    		 DNA/RNA Synthesis Cancer
    Thio-ITP (6-Thioinosine 5′-triphosphate) is an RNA polymerase activity competitive inhibitor. Thio-ITP has a high apparent affinity for the polymerases (RNA polymerase I Ki: 40.9 μM; RNA polymerase II Ki: 38.0 μM) .
    Thio-ITP
  • HY-134278A
    8-Bromoinosine-5'-O-triphosphate tetrasodium

    8-Br-ITP tetrasodium; 8-Bromo ITP tetrasodium

    		 Nucleoside Antimetabolite/Analog Others
    8-Bromoinosine-5'-O-triphosphate (8-Br-ITP) tetrasodium is a derivative of the nucleoside triphosphate Inosine-5'-triphosphate (ITP) (HY-W013706). 8-Bromoinosine-5'-O-triphosphate tetrasodium can be used in the determination of nucleoside diphosphate kinase (NDPK) activity .
    8-Bromoinosine-5'-O-triphosphate tetrasodium
  • HY-173532
    2-Methylthio TNP-ITP tetrasodium

    2-Methylthio TNP-Inosine 5'-triphosphate tetrasodium

    		 Fluorescent Dye Others
    2-Methylthio TNP-ITP (2-Methylthio TNP-Inosine 5'-triphosphate) tetrasodium is a fluorescent derivative of inosine triphosphate (ITP) with a TNP (2,4,6-trinitrophenyl) fluorophore .
    2-Methylthio TNP-ITP tetrasodium
  • HY-173533
    2-Chloro TNP-ITP tetrasodium

    2-Chloro TNP-Inosine 5'-triphosphate tetrasodium

    		 Drug Derivative Others
    2-Chloro TNP-ITP (2-Chloro TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
    2-Chloro TNP-ITP tetrasodium
  • HY-173531
    8-Bromo TNP-ITP tetrasodium

    8-Bromo TNP-Inosine 5'-triphosphate tetrasodium

    		 Drug Derivative Others
    8-Bromo TNP-ITP (8-Bromo TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
    8-Bromo TNP-ITP tetrasodium
  • HY-170506
    KB-208

    		Others Inflammation/Immunology
    KB-208 is a phagocytosis inhibitor that improves immune thrombocytopenia (ITP) in mouse models at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum toxicity biomarkers. KB-208 can be used in immunology research .
    KB-208

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