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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

IL-15 Antibody

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

7

Inhibitory Antibodies

Cat. No. Product Name Target Research Area
  • HY-P990223
    Anti-Mouse IL-15 Antibody (AIO.3)

    		Inhibitory Antibodies Others
    Anti-Mouse IL-15 Antibody (AIO.3) is a rat-derived IgG2a, λ type antibody inhibitor, targeting to mouse IL-15.
  • HY-P99661
    Inbakicept

    		Interleukin Related Cancer
    Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an IL-15 superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells .
  • HY-P99410
    Ordesekimab

    AMG 714; PRV-015

    		 Interleukin Related Inflammation/Immunology
    Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) .
  • HY-P99850
    Depemokimab

    GSK-3511294

    		 Interleukin Related Inflammation/Immunology
    Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma .
  • HY-P990446
    Anti-IL-15 Antibody (DISC0280)

    DISC0280

    		 Interleukin Related Inflammation/Immunology
    The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets IL-15. The Anti-IL-15 Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-P99759
    Nogapendekin alfa (his tag)

    IL-15N72D

    		 Interleukin Related Inflammation/Immunology Cancer
    Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 + T cells .
  • HY-P990719
    Efbalropendekin alfa

    XmAb24306

    		 Interleukin Related Inflammation/Immunology Cancer
    Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro .

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