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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

IL-15 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (8)
By Research Areas:	Cancer (5) Infection (2) Inflammation/Immunology (7) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: 15-PGDH ADC Antibody Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) Enteropeptidase Interleukin Related EHD Protein IRAK ADC Linker PROTAC-Linker Conjugates for PAC Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990223

Anti-Mouse IL-15 Antibody (AIO.3)	Interleukin Related	Infection Others Inflammation/Immunology Cancer
Anti-Mouse IL-15 Antibody (AIO.3) is a rat-derived IgG2a, λ type antibody inhibitor, targeting to mouse IL-15.

HY-P990446

*Anti-IL-15* Antibody (DISC0280)** DISC0280	Interleukin Related	Inflammation/Immunology
The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets *IL-15. The Anti-IL-15* Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99661

Inbakicept 1 Publications Verification	Interleukin Related	Cancer
Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an *IL-15* superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells .

HY-P99410

Ordesekimab AMG 714; PRV-015	Interleukin Related	Inflammation/Immunology
Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) .

HY-P99759

Nogapendekin alfa (his tag) IL-15N72D	Interleukin Related	Inflammation/Immunology Cancer
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of *IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15* cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 ⁺ T cells .

HY-P99850

Depemokimab GSK-3511294	Interleukin Related	Inflammation/Immunology
Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma .

HY-P990808

Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1)	Interleukin Related	Infection Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) is a rat-derived IgG2b κ type antibody inhibito, targeting to mouse CD122/IL-2Rβ. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can block IL-2 and IL-15. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can deplete natural killer (NK) cells and NKT cells. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as melanoma, experimental autoimmune encephalomyelitis (EAE) and diabetes .

HY-P990719

Efbalropendekin alfa XmAb24306	Interleukin Related	Inflammation/Immunology Cancer
Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro .

Cat. No.	Product Name	Target	Research Area

HY-P990223

Anti-Mouse IL-15 Antibody (AIO.3)	Interleukin Related	Infection Others Inflammation/Immunology Cancer
Anti-Mouse IL-15 Antibody (AIO.3) is a rat-derived IgG2a, λ type antibody inhibitor, targeting to mouse IL-15.

HY-P990446

*Anti-IL-15* Antibody (DISC0280)** DISC0280	Interleukin Related	Inflammation/Immunology
The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets *IL-15. The Anti-IL-15* Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99661

Inbakicept 1 Publications Verification	Interleukin Related	Cancer
Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an *IL-15* superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells .

HY-P99410

Ordesekimab AMG 714; PRV-015	Interleukin Related	Inflammation/Immunology
Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) .

HY-P99759

Nogapendekin alfa (his tag) IL-15N72D	Interleukin Related	Inflammation/Immunology Cancer
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of *IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15* cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 ⁺ T cells .

HY-P99850

Depemokimab GSK-3511294	Interleukin Related	Inflammation/Immunology
Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma .

HY-P990808

Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1)	Interleukin Related	Infection Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) is a rat-derived IgG2b κ type antibody inhibito, targeting to mouse CD122/IL-2Rβ. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can block IL-2 and IL-15. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can deplete natural killer (NK) cells and NKT cells. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as melanoma, experimental autoimmune encephalomyelitis (EAE) and diabetes .

HY-P990719

Efbalropendekin alfa XmAb24306	Interleukin Related	Inflammation/Immunology Cancer
Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P84532

	CD215 Antibody (YA4229) IL15RA	WB, ELISA	Human
	CD215 Antibody (YA4229) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD215.

HY-P84102

	CD122 Antibody (YA3799) IL2RB; IL15RB; P70-75	FC, ELISA	Human
	CD122 Antibody (YA3799) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD122.

HY-P87543

	IL-15 Antibody (YA7227)	WB	Human

HY-P87327

	IL-15RA Antibody (YA7010) AA690181 Antibody; CD215 Antibody; I15RA_HUMAN Antibody; IL 15R alpha Antibody; IL-15 receptor subunit alpha Antibody; IL-15R-alpha Antibody; IL-15RA Antibody; IL15ra Antibody; Interleukin 15 receptor alpha Antibody; Interleukin 15 receptor subunit alpha Antibody	WB, ICC/IF	Human
	IL-15RA Antibody (YA7010) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-15RA.

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