Human IgE

By Targets:	Antibiotic (1) Apoptosis (3) Bacterial (2) Biochemical Assay Reagents (1) Fungal (1) Glutathione S-transferase (1) Interleukin Related (4) Parasite (1) STAT (1) TNF Receptor (1)
By Research Areas:	Cancer (3) Infection (2) Inflammation/Immunology (10)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99313

Quilizumab Anti-Human IGHE Recombinant Antibody	Apoptosis	Inflammation/Immunology
Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed *IGHE/IgE, leading to IGHE/IgE* switching and memory B cell depletion. Quilizumab has potential in asthma research .

HY-P9950

Omalizumab 1 Publications Verification Olizumab; rhuMab-E25	Interleukin Related	Inflammation/Immunology Cancer
Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research .

HY-A0059

Nifuratel 3 Publications Verification NF 113; SAP 113; Methylmercadone	Bacterial Parasite Antibiotic Fungal Apoptosis STAT Interleukin Related TNF Receptor	Infection Inflammation/Immunology Cancer
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .

HY-NP201

Human immunoglobulin E Human IgE	Biochemical Assay Reagents	Inflammation/Immunology
Human immunoglobulin E (Human IgE) is a key mediator in allergic diseases. Human immunoglobulin E is made up of heavy (H) and light (L) chains, of which the variable (V) domains of the H chains are believed to contribute much to their antigenbinding properties .

HY-P990959

Lesigercept	Apoptosis	Inflammation/Immunology
Lesigercept is a recombinant fusion protein comprising an *FcERI (IgE* Fc receptor subunit alpha)** fused to a human IgG4 Fc .

HY-165484

AVP-13358	Interleukin Related	Inflammation/Immunology
AVP-13358 is an orally active *IgE* inhibitor that effectively suppresses immunoglobulin E (IgE)-mediated immune responses, with IC₅₀ values of 8 and 3 nM for *IgE* inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell *IgE* receptor (CD23) in human monocytes and the CD23 and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses .

HY-P991256

FB-825	Interleukin Related	Inflammation/Immunology
FB-825 is a human monoclonal antibody (mAb) targeting IGHE. FB-825 targets the CεmX domain of membrane IgE (mIgE), resulting in the downregulation of mIgE-positive B cells and the production of IgE. FB-825 can be used in Allergic asthma, Atopic dermatitis, Job syndrome and Allergic rhinitis research .

HY-N12261

Benastatin B	Glutathione S-transferase Bacterial	Infection Inflammation/Immunology Cancer
Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC₅₀ of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC₅₀ of 79 μg/mL .

Cat. No.	Product Name	Type

HY-NP201

Human immunoglobulin E Human IgE	Native Proteins
Human immunoglobulin E (Human IgE) is a key mediator in allergic diseases. Human immunoglobulin E is made up of heavy (H) and light (L) chains, of which the variable (V) domains of the H chains are believed to contribute much to their antigenbinding properties .

Cat. No.	Product Name	Target	Research Area

HY-P3746

Pentigetide	Peptides	Inflammation/Immunology
Pentigetide is a sythsis pepetide (Asp-Ser-Asp-Pro-Arg or D-S-D-P-R), also know as “HEPP” for “Human IgE Pentapeptide”. Pentigetide can not produce IgE inhibition in several different systems, due to the aspartic acids in HEPP changed into an asparagine .

Cat. No.	Product Name

HY-K0213

Protein A Agarose 1 Publications Verification
MCE Protein A Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein A, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG, IgE, IgM.

Cat. No.	Product Name	Target	Research Area

HY-P99313

Quilizumab Anti-Human IGHE Recombinant Antibody	Apoptosis	Inflammation/Immunology
Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed *IGHE/IgE, leading to IGHE/IgE* switching and memory B cell depletion. Quilizumab has potential in asthma research .

HY-P9950

Omalizumab 1 Publications Verification Olizumab; rhuMab-E25	Interleukin Related	Inflammation/Immunology Cancer
Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research .

HY-P99319

Talizumab TNX 901; Anti-Human IgE Fc Recombinant Antibody	Inhibitory Antibodies	Inflammation/Immunology
Talizumab (TNX 901) is an anti-IgE humanized IgG1 monoclonal antibody .

HY-P990959

Lesigercept	Apoptosis	Inflammation/Immunology
Lesigercept is a recombinant fusion protein comprising an *FcERI (IgE* Fc receptor subunit alpha)** fused to a human IgG4 Fc .

HY-P991256

FB-825	Interleukin Related	Inflammation/Immunology
FB-825 is a human monoclonal antibody (mAb) targeting IGHE. FB-825 targets the CεmX domain of membrane IgE (mIgE), resulting in the downregulation of mIgE-positive B cells and the production of IgE. FB-825 can be used in Allergic asthma, Atopic dermatitis, Job syndrome and Allergic rhinitis research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12261

Benastatin B	Structural Classification Microorganisms Source classification Phenols Polyphenols	Glutathione S-transferase Bacterial
Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC₅₀ of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC₅₀ of 79 μg/mL .

Species:	Human (10)
Tag:	His (7) SUMO (1) Tag Free (2) Avi (1) Fc (1)
Source:	HEK293 (7) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P73907

	IgE Protein, Human (HEK293, His) Immunoglobulin heavy constant epsilon; IGHE; IgE	Human	HEK293
	IgE protein is an important immunoglobulin component that participates in the recognition and effector phases of humoral immunity. As a membrane-bound receptor on B lymphocytes, IgE triggers clonal expansion upon antigen binding, leading to plasma cell differentiation. IgE Protein, Human (HEK293, His) is the recombinant human-derived IgE protein, expressed by HEK293 , with C-His labeled tag.

HY-P700736

	IgE Protein, Human (HEK293, His-Avi) Ig epsilon chain C region; IgE	Human	HEK293
	IgE protein is an important immunoglobulin component that participates in the recognition and effector phases of humoral immunity. As a membrane-bound receptor on B lymphocytes, IgE triggers clonal expansion upon antigen binding, leading to plasma cell differentiation. IgE Protein, Human (HEK293, His-Avi) is the recombinant human-derived IgE protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P72191

	*Fc epsilon RIA/FCER1A Protein, Human* (His-SUMO)** Fc epsilon RI alpha; Fc epsilon RI alpha chain ; high affinity I; receptor for; alpha subunit; Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide; Fc IgE receptor; alpha chain; Fc IgE receptor; alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER1A; Fcer1a; FCERA_Human; FceRI alpha; FcERI; high affinity IgE receptor;	Human	E. coli
	The Fc epsilon RIA/FCER1A protein is a high-affinity receptor for IgE and critically mediates IgE effector function in myeloid cells. After binding to IgE and cross-linking with antigen, it activates signaling pathways that induce myeloid cell activation and differentiation. Fc epsilon RIA/FCER1A Protein, Human (His-SUMO) is the recombinant human-derived Fc epsilon RIA/FCER1A protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P70309

	Galectin-3/LGALS3 Protein, Human 2 Publications Verification rHuGalectin-3; Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 AntIgEn; LGALS3; MAC2	Human	E. coli
	Galectin-3/LGALS3 Protein is a type of galactoside-binding lectin that has a high binding affinity for carbohydrates with β-galactoside linkages. Galectin-3/LGALS3 Protein interacts with glycosylated proteins to mediate intercellular interactions and adhesion to the extracellular matrix. Galectin-3/LGALS3 Protein plays various roles, including regulating signaling pathways such as Wnt/β-catenin, affecting cell proliferation and survival, modulating immune functions, and influencing tumor progression. Galectin-3/LGALS3 Protein, Human is a recombinant galectin-3/LGALS3 protein expressed in E. coli.

HY-P700079AF

	*Animal-Free Galectin-3/LGALS3 Protein, Human* (His)** Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 AntIgEn; LGALS3; MAC2	Human	E. coli
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Animal-Free Galectin-3/LGALS3 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-3/LGALS3 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P70171

	*Galectin-3/LGALS3 Protein, Human* (HEK293, His)** rHuGalectin-3/LGALS3, His; Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP 35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 AntIgEn; LGALS3; MAC2	Human	HEK293
	The Galectin-3/LGALS3 protein is a galactose-specific lectin known for its diverse roles in cellular processes. It binds IgE and synergizes with α-3 and β-1 integrins to promote CSPG4-induced endothelial cell migration. Galectin-3/LGALS3 Protein, Human (HEK293, His) is the recombinant human-derived Galectin-3/LGALS3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704671

	IgE Protein, Human (322a.a, HEK293, His) Ig epsilon chain C region; IgE	Human	HEK293

HY-P703902

	*Fc epsilon RIA/FCER1A Protein, Human* (HEK293,His)** Fc epsilon RI alpha; Fc epsilon RI alpha chain ; high affinity I; receptor for; alpha subunit; Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide; Fc IgE receptor; alpha chain; Fc IgE receptor; alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER1A; Fcer1a; FCERA_Human; FceRI alpha; FcERI; high affinity IgE receptor;	Human	HEK293

HY-P703903

	*Fc epsilon RIA/FCER1A Protein, Human* (HEK293)** Fc epsilon RI alpha; Fc epsilon RI alpha chain ; high affinity I; receptor for; alpha subunit; Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide; Fc IgE receptor; alpha chain; Fc IgE receptor; alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER1A; Fcer1a; FCERA_Human; FceRI alpha; FcERI; high affinity IgE receptor;	Human	HEK293

HY-P704589

	*Fc epsilon RIA/FCER1A Protein, Human* (Active, HEK293, Fc)** Fc epsilon RI alpha; Fc epsilon RI alpha chain ; high affinity I; receptor for; alpha subunit; Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide; Fc IgE receptor; alpha chain; Fc IgE receptor; alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER1A; Fcer1a; FCERA_Human; FceRI alpha; FcERI; high affinity IgE receptor	Human	HEK293

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HY-P80404

	Galectin 3 Antibody (YA421) Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; GAL-3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antIgEn; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387; LEG3_Human.	WB, ICC/IF, FC, IHC-P	Human, Mouse
	Galectin 3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 26 kDa, targeting to Galectin 3. It can be used for WB,ICC/IF,FC,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P84977

	CD23 Antibody (YA4669) Blast 2 antibody; BLAST-2 antibody; Blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4; member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antIgEn antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon receptor II antibody; Fc epsilon RII antibody; Fc fragment of IgE antibody; Fc fragment of IgE low affinity II receptor for antibody; Fc fragment of IgE receptor II antibody; Fc fragment of IgE; low affinity II; receptor for; CD23; antibody; Fc of IgE antibody; Fc of IgE; low affinity II; receptor for; CD23; antibody; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor; IgE; low affinity II; alpha polypeptide; isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_Human antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IgEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor antibody; Immunoglobulin E receptor; low affinity II antibody; Immunoglobulin E-binding factor antibody; Immunoglobulin epsilon chain antibody; LEUKOCYTE ANTIgEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antIgEn CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody; CD23 nanobody	ELISA, FC	Human

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Human IgE

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