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Results for "

Hrd1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-49116
    CP26

    		E1/E2/E3 Enzyme Infection Inflammation/Immunology
    CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1].
    CP26
  • HY-B0124
    Zonisamide
    1 Publications Verification

    AD 810; CI 912

    		 Carbonic Anhydrase Apoptosis Neurological Disease
    Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
    Zonisamide
  • HY-160700
    TNG348

    		Deubiquitinase JNK Cancer
    TNG348 is an orally available allosteric inhibitor of the ubiquitin-specific protease USP1. TNG348 specifically and efficiently inhibits the activity of USP1, inhibiting its deubiquitination of proliferative PCNA and FANCD2, thereby disrupting the DNA repair process. TNG348 has inhibitory activity against breast and ovarian cancers carrying BRCA1/2 mutations and other homologous recombination defects (HRD) .
    TNG348
  • HY-B0124A
    Zonisamide sodium

    AD 810 sodium; CI 912 sodium

    		 Carbonic Anhydrase Apoptosis Cardiovascular Disease Neurological Disease
    Zonisamide (AD 810) sodium is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide sodium exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide sodium also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide sodium can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
    Zonisamide sodium
  • HY-B0124R
    Zonisamide (Standard)

    AD 810 (Standard); CI 912 (Standard)

    		 Reference Standards Carbonic Anhydrase Apoptosis Neurological Disease
    Zonisamide (Standard) is the analytical standard of Zonisamide. This product is intended for research and analytical applications. Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
    Zonisamide (Standard)
  • HY-B0124S2
    Zonisamide-13C6

    AD 810-13C6; CI 912-13C6

    		 Isotope-Labeled Compounds Carbonic Anhydrase Apoptosis Neurological Disease
    Zonisamide- 13C6 (AD 810- 13C6) is 13C labeled Zonisamide. Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy [1] .
    Zonisamide-13C6
  • HY-RS14127
    SYVN1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SYVN1 Human Pre-designed siRNA Set A contains three designed siRNAs for SYVN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SYVN1 Human Pre-designed siRNA Set A
    SYVN1 Human Pre-designed siRNA Set A
  • HY-RS18845
    Syvn1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Syvn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Syvn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Syvn1 Mouse Pre-designed siRNA Set A
    Syvn1 Mouse Pre-designed siRNA Set A

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