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High density lipoprotein (human)

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By Targets:	Apolipoprotein (2) NO Synthase (1)
By Research Areas:	Cardiovascular Disease (1) Inflammation/Immunology (1)

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Targets Recommended: LDLR LOX-1 HMG Family

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-NP203

High density lipoprotein (human) HDL (human)	Apolipoprotein NO Synthase	Cardiovascular Disease
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

HY-165061

5(Z),11(Z),14(Z)-Eicosatrienoic acid Sciadonic acid	Apolipoprotein	Inflammation/Immunology
5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid), a polyunsaturated fatty acid sourced from maritime pine seed oil, gymnospermae leaves and seeds, and freshwater gastropods, has been shown to reduce high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1 when included in their diet. In vitro studies indicate that it diminishes cholesterol efflux, and when applied topically in its methyl ester form, it alleviates inflammatory processes, likely by displacing arachidonic acid from phospholipid pools and lowering concentrations of downstream inflammatory mediators such as prostaglandin E2 and leukotrienes.

Cat. No.	Product Name	Type

HY-NP203

High density lipoprotein (human) HDL (human)	Native Proteins
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

High density lipoprotein (human)

HDL (human)

Native Proteins

High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

Cat. No.	Compare	Product Name	Species	Source

HY-P70873

	GPIHBP1 Protein, Human (HEK293, Fc) glycosylphosphatidylinositol-anchored High density lipoprotein-binding protein1; GPI anchored High density lipoprotein binding protein 1; GPI-Anchored HDL-Binding Protein 1; GPIHBP1; GPI-HBP1; GPI-HBP1LOC338328; HBP1; High density lipoprotein-binding protein 1; H	Human	HEK293
	The GPIHBP1 protein mediates lipid metabolism by transporting lipoprotein lipase LPL, anchoring it in capillaries, and preventing loss of activity. It has a crucial role in chylomicron lipolysis, triglyceride metabolism, and overall lipid homeostasis. GPIHBP1 Protein, Human (HEK293, Fc) is the recombinant human-derived GPIHBP1 protein, expressed by HEK293 , with C-hFc labeled tag.

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