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Pathways Recommended: Vitamin D Related/Nuclear Receptor
Results for "

Hepatocyte nuclear factor 4 alpha

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108469
    BI-6015
    5 Publications Verification

    		 Orphan Receptor Metabolic Disease Cancer
    BI-6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BI6015 represses insulin promoter activity through HNF4α antagonism. BI-6015 can be used for the research of cancer and diabetes .
    BI-6015
  • HY-119971
    BIM5078

    		Nuclear Hormone Receptor 4A/NR4A Metabolic Disease Cancer
    BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes .
    BIM5078
  • HY-176847
    HNF4A-IN-1

    		Orphan Nuclear Receptor Apoptosis Cancer
    HNF4A-IN-1 (Compound 17) is a Hepatocyte nuclear factor 4 alpha (HNF4A) inhibitor. HNF4A-IN-1 has potent anticancer activity against human head and neck squamous cells (SCC131 cells) and with no toxicity to normal cells. HNF4A-IN-1 significantly inhibits SCC131 cells growth with an IC50 of 1.75 μM, and induces apoptosis and G2/M cell cycle arrest. HNF4A-IN-1 promotes tumor regression in SCC131 tumor xenografts mouse models .
    HNF4A-IN-1

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