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Results for "

HDAC degrader1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132998
    HDAC6 degrader-1

    		PROTACs HDAC Cancer
    HDAC6 degrader-1 (Compound NP8) is the PROTAC degrader for HDAC6 with a DC50 of 3.8 nM in cell MM.1S .(Blue: ligand for E3 ligase Pomalidomide (HY-10984); Black: linker (HY-140213); Pink: ligand for target protein Nexturastat A (HY-16699))
    HDAC6 degrader-1
  • HY-176207
    HDAC degrader-1

    		ByeTAC HDAC Cancer
    HDAC6 degrader-6 (compound 10c) is a ByeTAC protein degrader targeting HDAC6, with IC50 values of 0.034 μM, 0.166 μM, 0.703 μM, and 0.293 μM for HDAC6, HDAC1, HDAC2, and HDAC3, respectively. HDAC6 degrader-6 induces cell apoptosis and can be used for the study of multiple myeloma(USP14 ligand: HY-159808; HDAC ligand: HY-176209; linker: HY-W016871)
    HDAC degrader-1
  • HY-157216
    HDAC1 Degrader-1

    		HDAC Cancer
    HDAC1 Degrader-1 (compound 1a) is an HDAC1 degrader with anticancer activity. HDAC1 Degrader-1 significantly reduces HDAC1 levels in MM.1S multiple myeloma cells .
    HDAC1 Degrader-1
  • HY-163920
    PROTAC HDAC8 Degrader-1

    		PROTACs HDAC Cancer
    Degrader-1 (compound Z16) is a potent and selective HDAC8 PROTAC degrader with an DC50 of 0.27 nM in A549 cells .
    PROTAC HDAC8 Degrader-1
  • HY-152133
    PROTAC HDAC6 degrader 1

    		PROTACs HDAC Apoptosis Cancer
    PROTAC HDAC6 degrader (Compound A6) is a potent and selective PROTAC HDAC6 degrader with a DC50 of 3.5 nM. PROTAC HDAC6 degrader shows promising antiproliferative activity via inducing apoptosis in myeloid leukemia cell lines .
    PROTAC HDAC6 degrader 1
  • HY-155398
    PRO-HD3

    		PROTACs HDAC Cancer
    PRO-HD3 is a cell-specific, PROTAC-based HDAC6 degrader .
    PRO-HD3
  • HY-155397
    PRO-HD2

    		PROTACs HDAC Cancer
    PRO-HD2 is a cell-specific, PROTAC-based HDAC6 degrader .
    PRO-HD2

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