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Results for "

GTP analogue

" in MedChemExpress (MCE) Product Catalog:

9

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155600
    5′-Guanylyl methylenediphosphonate sodium

    β,γ-Methylene-GTP sodium

    		 Nucleoside Antimetabolite/Analog Others
    5′-Guanylyl methylenediphosphonate (sodium) is a GTP analogue and a specific, competitive inhibitor of the GTP reaction in protein synthesis .
    5′-Guanylyl methylenediphosphonate sodium
  • HY-137167
    Guanylyl imidodiphosphate lithium

    Gpp(NH)p lithium

    		 Adenylate Cyclase Endocrinology
    Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity .
    Guanylyl imidodiphosphate lithium
  • HY-W013706
    Inosine-5'-triphosphate trisodium salt

    ITP trisodium salt; Inosine triphosphate trisodium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt
  • HY-131598
    6-Thio-GTP

    6-Thioguanosine-5'-triphosphate

    		 Ras Inflammation/Immunology Cancer
    6-Thio-GTP is an analogue of GTP, and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256) .
    6-Thio-GTP
  • HY-100767
    Guanylyl Imidodiphosphate trisodium

    Guanosine 5'-[β,γ-imido]triphosphate trisodium

    		 Adenylate Cyclase Endocrinology
    Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .
    Guanylyl Imidodiphosphate trisodium
  • HY-137614C
    Rp-GTPαS tetrasodium

    		Nucleoside Antimetabolite/Analog Others
    Rp-GTPαS tetrasodium is a phosphorothioate analogue of Guanosine triphosphate (GTP) (HY-113225) that can activate calcium release and secretion in single rat peritoneal mast cells .
    Rp-GTPαS tetrasodium
  • HY-173530
    8-Bromo TNP-GTP tetrasodium

    8-Bromo TNP-Guanosine 5'-triphosphate tetrasodium

    		 Fluorescent Dye Others
    8-Bromo TNP-GTP (8-Bromo TNP-Guanosine 5'-triphosphate) tetrasodium is a fluorescent TNP-GTP analogue with a TNP fluorophore and a bromo group at the 8-position. 8-Bromo TNP-GTP tetrasodium can be used to analyze the binding activity of GTP-binding proteins (such as Ras and Gα subunits) .
    8-Bromo TNP-GTP tetrasodium
  • HY-168351
    Fluorphine

    		Opioid Receptor Neurological Disease
    Fluorphine is an analogue of Brorphine and can bind to μ-opioid receptor (MOR) (Ki: 12.5 nM). Fluorphine has GTPγS binding (EC50: 75 nM) and βarrestin 2 recruitment (EC50: 377 nM) activity. Fluorphine induces respiratory depressant effects .
    Fluorphine
  • HY-150172A
    Inosine 5'-triphosphate lithium salt

    ITP lithium salt; Inosine triphosphate lithium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
    Inosine 5'-triphosphate lithium salt

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