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GSK-3β-IN-28

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175850
    GSK-3β-IN-28

    		GSK-3 Apoptosis NF-κB c-Myc Cancer
    GSK-3β inhibitor 28 is selective and non-competitivea glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 14.82 nM. GSK-3β inhibitor 28 can upregulate the expression level of phosphorylated GSK-3β and downregulate the expression of p-NF-κB, P65, C-myc and Cyclin D1. GSK-3β inhibitor 28 can induce cells apoptosis, G1 phase arrest and inhibit migration. GSK-3β inhibitor 28 can be used for the research of cancer, such as colorectal cancer .
    GSK-3β-IN-28

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