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Results for "

GI absorption

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-152136
    Antituberculosis agent-6

    		Bacterial Fungal Infection
    Antituberculosis agent-6 (compound 9g) is a potent antimycobacterial agent. Antituberculosis agent-6 shows significant activity against M. tuberculosis, with a MIC of 3.49 μM. Antituberculosis agent-6 also shows good antifungal activity against A. niger, with a MIC of 62.50 μM. Antituberculosis agent-6 shows high GI absorption .
    Antituberculosis agent-6
  • HY-162373
    α-Amylase/α-Glucosidase-IN-10

    		Amylases Glycosidase P-glycoprotein Metabolic Disease
    α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an α-amylase and α-glucosidase inhibitor (IC50: 30.39 μM and 65.1 μM) with potential diabetes inhibitory effects. α-Amylase/α-Glucosidase-IN-10 exhibits high gastrointestinal (GI) absorption in ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) prediction. While α-Amylase/α-Glucosidase-IN-10 acts as a substrate for P-gp and does not cross the blood-brain barrier (BBB), there may be a risk of central nervous system side effects .
    α-Amylase/α-Glucosidase-IN-10
  • HY-177063
    IL-6-IN-2

    		Interleukin Related Others
    IL-6-IN-2 (Compound 15) is an inhibitor of the IL-6/IL-6R protein interaction. The ∆G binding energy of IL-6-IN-2 is −36.50 kcal/mol. Contributions of Lys66, Phe74, Gln175, Ser176, and Arg179 to IL-6 binding are −1.10, −8.68, −6.91, −3.69, and −1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption .
    IL-6-IN-2

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