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Fedratinib hydrochloride hydrate (Standard)

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10409AR
    Fedratinib hydrochloride hydrate (Standard)

    TG-101348 hydrochloride hydrate (Standard); SAR 302503 hydrochloride hydrate (Standard)

    		 JAK Apoptosis Cancer
    Fedratinib (hydrochloride hydrate) (Standard) is the analytical standard of Fedratinib (hydrochloride hydrate). This product is intended for research and analytical applications. Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research .
    Fedratinib hydrochloride hydrate (Standard)
  • HY-10409R
    Fedratinib (Standard)

    TG-101348 (Standard); SAR 302503 (Standard)

    		 JAK Apoptosis Cancer
    Fedratinib (Standard) is the analytical standard of Fedratinib. This product is intended for research and analytical applications. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research .
    Fedratinib (Standard)

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