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Results for "

FRET-based

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Fluorescent Dye

4

Peptides

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1859
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide

    		Fluorescent Dye Others
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide
  • HY-D1046
    Dabcyl acid, SE

    Dabcyl, SE

    		 Fluorescent Dye Metabolic Disease
    Dabcyl acid, SE is the amino-reactive form of Dabcyl acid (DABCYL), and widely used to prepare a variety of FRET-based probes that contain DABCYL.
    Dabcyl acid, SE
  • HY-P11302
    DABCYL-RAGGYIFS-(E-EDANS)-NH2

    		CHIKV Virus Protease Infection
    DABCYL-RAGGYIFS-(E-EDANS)-NH2, an octapeptide, is a FRET-based substrate peptide of CHIKV nsP2protease with highly sensitivity. DABCYL-RAGGYIFS-(E-EDANS)-NH2 can be cleaved by the active CHIKV nsP2protease, separating fluorophore and quencher and resulting in an increase of fluorescence signal. DABCYL-RAGGYIFS-(E-EDANS)-NH2 can used for the determination of CHIKV nsP2protease activity .
    DABCYL-RAGGYIFS-(E-EDANS)-NH2
  • HY-D1079
    EDANS sodium

    		DNA Stain Others
    EDANS sodium is a potent fluorogenic substrates. EDANS sodium is a donor for FRET-based nucleic acid probes and protease substrates. EDANS sodium is often paired with DABCYL or DABSYL. The optimal absorbance and emission wavelengths of EDANS sodium are λabs = 336 nm and λem = 490 nm respectively .
    EDANS sodium
  • HY-P1859A
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide acetate

    		Biochemical Assay Reagents Others
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide (acetate) is synthesized from MCA-SEVNLDAEFR-K(Dnp)-RR, amide (HY-P1859) by losing the H of the -OH group of acetic acid. MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide acetate
  • HY-P5415
    DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS

    		HIV Others
    DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-kD protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
    DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
  • HY-162282
    PROTAC METTL3-14 degrader 1

    		PROTACs DNA Methyltransferase Cancer
    PROTAC METTL3-14 degrader 1 (compound 30) is a PROTAC degrader of METTL3-14. PROTAC METTL3-14 degrader 1 shows a 50% or higher degradation of METTL3 and/or METTL14(Pink: Ligand for target protein (HY-115717); Black: Linker (HY-168686); Blue: Ligand for E3 ligase (HY-10984)) .
    PROTAC METTL3-14 degrader 1
  • HY-176347S
    Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2

    		Isotope-Labeled Compounds Cancer
    Alpha Feto Protein, Arg- 13C36, 15N4, Lys- 13C6, 15N2 is the 13C- and 15N-labeled Alpha Feto Protein.
    Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2

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