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Results for "

FKBP12 ligand-1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153806
    RapaBlock

    ZZY05-092

    		 FKBP Cancer
    RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand .
    RapaBlock
  • HY-114434
    AP1867
    3 Publications Verification

    		 FKBP Cancer
    AP1867 is a synthetic FKBP12 F36V-directed ligand .
    AP1867
  • HY-170988
    FKBP12 ligand-1

    		FKBP Ligands for Target Protein for PROTAC Cancer
    FKBP12 ligand-1 is a targeting protein ligand of MC-25B (HY-170983), which is a specific FKBP12 PROTAC [1].
    FKBP12 ligand-1
  • HY-173082
    10-SLF

    		PROTACs FKBP Cancer
    10-SLF is a PROTAC FKBP12 degrader. 10-SLF induces a ternary complex between FKBP12 and FBXW7-R465C, and promotes FBXW7-R465C-dependent proteasomal degradation of FKBP12. 10-SLF selectively reduces FKBP12 levels in cells expressing FBXW7-R465C. Pink: FKBP12 ligand (HY-170988); Black: linker (HY-W004640); Blue: E3 ligase ligand .
    10-SLF
  • HY-172265
    FKBP12 PROTAC FM4

    		PROTACs Cancer
    FKBP12 PROTAC FM4 is a PROTAC degrader of MTH1, with a DC50 values of 0.09–0.22 nM. FKBP12 PROTAC FM4 is composed of PROTAC target protein ligand AP1867-3-(aminoethoxy) (HY-129363) (red part), E3 ligase ligand MTH1 ligand 1 (HY-134724) (blue part) and PROTAC Linker t-Boc-N-amido-PEG5-acetic acid (HY-W190962) (black part), among which the conjugate of PROTAC target protein ligand + Linker is FKBP12 Ligand-Linker Conjugate 2 (HY-172266) [1].
    FKBP12 PROTAC FM4

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