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Results for "

Exo-1

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Natural
Products

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112670
    Exo1
    5 Publications Verification

    		 Arf Family GTPase Others
    Exo1 is a chemical inhibitor of the exocytic pathway.
    Exo1
  • HY-P3187
    Exo-1,4-β-xylosidase

    		DNA/RNA Synthesis Others
    Exo-1,4-β-xylosidase is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. Exo-1,4-β-xylosidase is Ca 2+-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. Exo-1,4-β-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes [1] .
    Exo-1,4-β-xylosidase
  • HY-P2857
    Amyloglucosidase, Aspergillus niger

    Amyloglucosidase; 1,4-α-D-Glucan glucohydrolase; Exo-1,4-α-glucosidase

    		 Endogenous Metabolite Metabolic Disease
    Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry [1].
    Amyloglucosidase, Aspergillus niger
  • HY-170845
    MU1409

    		Endonuclease Cancer
    MU1409 is an inhibitor of MRE11 nuclease with an IC50 of 12.1 μM. Additionally, MU1409 also inhibits FEN1 and EXO1, with IC50 values of 24.2 and 176.4 μM, respectively. MU1409 affects DNA repair in cells, preventing the degradation of stalled replication forks in BRCA2-deficient cells, making it a promising candidate for research on BRCA2 mutation-induced cancers [1].
    MU1409
  • HY-RS20731
    Exo1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Exo1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Exo1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Exo1 Mouse Pre-designed siRNA Set A
    Exo1 Mouse Pre-designed siRNA Set A
  • HY-RS04585
    EXO1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EXO1 Human Pre-designed siRNA Set A contains three designed siRNAs for EXO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EXO1 Human Pre-designed siRNA Set A
    EXO1 Human Pre-designed siRNA Set A
  • HY-RS27243
    Exo1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Exo1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Exo1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Exo1 Rat Pre-designed siRNA Set A
    Exo1 Rat Pre-designed siRNA Set A
  • HY-174143
    EXO1-IN-1

    		Others Cancer
    EXO1-IN-1 (Compound F684) is a potent and selective inhibitor of exonuclease 1 (EXO1) (IC50= 15.7 μM). EXO1-IN-1 suppresses DNA end resection, promotes the accumulation of DNA double-strand breaks, and triggers S-phase PARylation, disrupts DNA repair pathways in homologous recombination-deficient (HRD) cancer cells, and selectively kills tumor cells with defects in HR genes like BRCA1/2. EXO1-IN-1 is promising for research of homologous recombination-deficient cancer (such as BRCA-related tumors) [1].
    EXO1-IN-1
  • HY-162274
    Oxazepine

    		Hedgehog Antibiotic Infection Cancer
    Oxazepine (compound 4a) has antimicrobial viability via binding OMPA/ exo-1,3-beta-glucanase proteins. Oxazepine is a hedgehog signaling inhibitor with antitumor viability [1].
    Oxazepine
  • HY-162273
    Antibacterial agent 189

    		Bacterial Smo Gli Infection Cancer
    Antibacterial agent 189 (compound 3a) is a potent antimicrobial agent. Antibacterial agent 189 offers high binding energy against the target OMPA/exo-1,3-beta-glucanase proteins. Antibacterial agent 189 exhibits the potent antimicrobial activities against E. coli, P. aeruginosa, S. aureus, B. subtilis, C. Albicans and A. flavus. Antibacterial agent 189 shows high binding energy against target SMO and SUFU/GLI-1 proteins [1].
    Antibacterial agent 189

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