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EcClpP

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175595

    ClpP Infection
    ADEP-14 is a bacterial ClpP activator with EC50s of 0.46 and 3.67  μM for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP). ADEP-14 binds to ClpP H sites and activates the protease. ADEP-14 has antibacterial activity. ADEP-14 can be used for bacterial infections research .
    ADEP-14
  • HY-175596

    ClpP Bacterial Infection
    ACP1-01 is a bacterial ClpP activator with EC50s of 3.4 and 2.6  μM for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP). ACP1-01 noncovalently binds to ClpP C sites and activates the protease. ACP1-01 has antibacterial activity. ACP1-01 can be used for bacterial infections research .
    ACP1-01
  • HY-175597

    ClpP Infection
    ClpP modulator-1 (Compound BC8a), a peptidomimetic, is an allosteric ClpP modulator. ClpP modulator-1 is a ClpP activator at low concentration with EC50s of 0.35 and 0.58  μM for for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP), resepectively. ClpP modulator-1 also inhibits peptidase activity at high concentration by competitively inhibiting substrate protein (LY-AMC) binding to ClpP C sites. ClpP modulator-1 has antibacterial activity. ClpP modulator-1 can be used for bacterial infections research .
    ClpP modulator-1

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